Gene · 6624
FSCN1: fascin actin-bundling protein 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. FSCN1: fascin actin-bundling protein 1. Genes, record 6624. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6624
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q16658 | Fascin | 493 | 28 | Ensembl, GeneID, HGNC |
Source UniProt
Patents44
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 45898 | Q16658 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 10546 | Q16658 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 5792 | Q16658 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 10546 | Q16658 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 5792 | Q16658 | Espacenet |
| JP 2024510632 A | 2024-03-08 | 2 | Q16658 | Espacenet |
| JP 2023123507 A | 2023-09-05 | 53 | Q16658 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 30797 | Q16658 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 133768 | Q16658 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 4198 | Q16658 | Espacenet |
1 to 10 of 44
See all 44 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,500
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | FSCN1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 11 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 9 | 2025 |
| P30CA076292 | Moffitt Cancer Center Support Grant | 8 | 2025 |
| P40OD010440 | Caenorhabditis Genetics Center | 7 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 6 | 2025 |
| P50CA126752 | SPORE in Lymphoma | 6 | 2025 |
| P30CA086862 | Cancer Center Support Grant | 5 | 2025 |
| P20GM103446 | Delaware INBRE | 4 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 4 | 2025 |
| R35GM122545 | The impact of dynamic actin polymerization on mitochondrial dynamics and function | 4 | 2025 |
1 to 10 of 1,500Source NIH's project files
See all 1,500 nih grantsPapers3,382
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| CaMKII generates actin bundle morphology and mechanics distinct from canonical bivalent cross-linkers. | bioRxiv | 2026 | 42817999 | PubTator, text mining | PubMed |
| FSCN1 Modulates Fatty Acid Metabolism and the Coordinated Activation of AKT/mTOR and p38 MAPK Pathways in Colorectal Cancer Cells. | Oncol Res | 2026 | 42769853 | PubTator, text mining | PubMed |
| The RNA-binding protein La/SSB is associated with HNSCC progression and TFAP2C/FSCN1-linked transcriptional regulation. | Oncogene | 2026 | 42693251 | PubTator, text mining | PubMed |
| Fascin-Centred Invasive Competence in Eutopic Endometrium: A Hypothesis-Driven Narrative Review of Endometriosis Pathogenesis and Non-Surgical Biomarker Potential. | Int J Mol Sci | 2026 | 42653239 | PubTator, text mining | PubMed |
| Fascin in dendritic protrusions is required for synaptic plasticity. | J Biol Chem | 2026 | 42617739 | PubTator, text mining | PubMed |
| [Expression of Concern] MicroRNA‑145‑5p suppresses fascin to inhibit the invasion and migration of cervical carcinoma cells. | Mol Med Rep | 2026 | 42596825 | PubTator, text mining | PubMed |
| State-dependent energy conversion produces degenerate dissipation in active actomyosin networks. | bioRxiv | 2026 | 42395412 | PubTator, text mining | PubMed |
| Synergistic assembly, disassembly, and protection of complex forms of bundled F-actin. | J Cell Biol | 2026 | 42384037 | PubTator, text mining | PubMed |
Integrative multi-omics and single-cell analysis identifies EGFR pathway activation and metabolic reprogramming as potential synthetic lethal vulnerabilities in resistance to the FGFR inhibitor AZD4547. | J Transl Med | 2026 | 42351126 | PubTator, text mining | PubMed |
| Fascin-1 expression in non-small cell lung cancer and its diagnostic implications. | Discov Oncol | 2026 | 42258099 | PubTator, text mining | PubMed |
1 to 10 of 3,382
See all 3,382 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/6624
GET https://conductscience.org/api/genes/v1/6624/patents?page=2