Gene · 6625
SNRNP70: small nuclear ribonucleoprotein U1 subunit 70
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. SNRNP70: small nuclear ribonucleoprotein U1 subunit 70. Genes, record 6625. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6625
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P08621 | U1 small nuclear ribonucleoprotein 70 kDa | 437 | 11 | Ensembl, GeneID, HGNC |
Source UniProt
Patents61
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 18021 | P08621 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 22369 | P08621 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 22369 | P08621 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 18021 | P08621 | Espacenet |
| JP 2024509935 A | 2024-03-05 | 34 | P08621 | Espacenet |
| US 11892452 B2 | 2024-02-06 | 59 | P08621 | Espacenet |
| US 11860162 B2 | 2024-01-02 | 1068 | P08621 | Espacenet |
| JP 2023123507 A | 2023-09-05 | 33 | P08621 | Espacenet |
| US 11694765 B2 | 2023-07-04 | 326 | P08621 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 79924 | P08621 | Espacenet |
1 to 10 of 61
See all 61 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,378
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | SNRNP70 papers | Newest fiscal year |
|---|---|---|---|
| ZIAES101074 | Environmental/genetic Risk Factors and Pathogenesis of Autoimmune Disease | 14 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 10 | 2025 |
| P30AR070254 | Johns Hopkins Rheumatic Diseases Resource-based Core Center (Johns Hopkins RDRCC) | 8 | 2025 |
| ZIAAR041203 | Muscle Disease Unit | 8 | 2025 |
| R01DK058110 | Dose-Dependent Effects of Hormone on the Activity of Estrogen Receptor Enhancers and Target Genes | 7 | 2025 |
| R01DK069710 | The Role of Nuclear PARPs in Signal-Regulated Transcription | 6 | 2025 |
| R01HL034594 | RISK FACTORS FOR CVD IN WOMEN | 6 | 2025 |
| T32AR048522 | Multidisciplinary Rheumatology Training Program | 6 | 2025 |
| P30CA014051 | Cancer Center Support (Core) Grant | 5 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
1 to 10 of 1,378Source NIH's project files
See all 1,378 nih grantsPapers2,902
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Widespread exon definition is promoted by the U1 snRNP 70K subunit and requires sites of contact with RNA Polymerase II. | bioRxiv | 2026 | 42818336 | PubTator, text mining | PubMed |
| The relationship between autoantibody and complement levels in the sera of patients with systemic lupus erythematosus. | Clin Immunol | 2026 | 42790660 | PubTator, text mining | PubMed |
| Prevalence and Clinical Associations of Systemic Sclerosis-Related Autoantibodies: A Nationwide Reuma.pt Cohort Study. | Antibodies (Basel) | 2026 | 42776798 | PubTator, text mining | PubMed |
| Utility of an extended 12-autoantibody panel in systemic sclerosis: Clinical and prognostic implications in a real-life cohort. | Rev Clin Esp (Barc) | 2026 | 42772597 | PubTator, text mining | PubMed |
| The association between cardiac arrhythmia and autoantibodies in systemic sclerosis. | Mod Rheumatol | 2026 | 42757877 | PubTator, text mining | PubMed |
| GPR56 and CD319 identify distinct cytotoxic-associated DP and DN T-cell subsets in early systemic lupus erythematosus. | Clin Rheumatol | 2026 | 42745124 | PubTator, text mining | PubMed |
| Cancer in Systemic Sclerosis: Clinical Associations and Prognostic Impact From the EUSTAR Registry. | Arthritis Rheumatol | 2026 | 42663235 | PubTator, text mining | PubMed |
| Wernicke's encephalopathy in mixed connective tissue disease triggered by persistent vomiting: a case report and literature review. | Rheumatol Int | 2026 | 42550248 | PubTator, text mining | PubMed |
| Fluorescence imaging-based investigation of tau-mediated promotion of U1 small nuclear ribonucleoprotein 70 kDa co-phase separation. | Int J Biol Macromol | 2026 | 42526554 | PubTator, text mining | PubMed |
| Evolution of Recurrent Myxofibrosarcoma of the Thoracic Wall at Single-Cell Resolution: A Case Report. | Int J Mol Sci | 2026 | 42511573 | PubTator, text mining | PubMed |
1 to 10 of 2,902
See all 2,902 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/6625
GET https://conductscience.org/api/genes/v1/6625/patents?page=2