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Gene · 6625

SNRNP70: small nuclear ribonucleoprotein U1 subunit 70

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SNRNP70: small nuclear ribonucleoprotein U1 subunit 70. Genes, record 6625. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6625

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Gene

Symbol
SNRNP70
HGNC
Name
small nuclear ribonucleoprotein U1 subunit 70
HGNC
NCBI Gene ID
6625
NCBI Gene
HGNC ID
HGNC:11150
HGNC
Ensembl
ENSG00000104852
NCBI Gene
Aliases
RNPU1Z, RPU1, SNRP70, Snp1, U1-70K, U170K, U1AP, U1RNP
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P08621U1 small nuclear ribonucleoprotein 70 kDa43711Ensembl, GeneID, HGNC

Source UniProt

Patents61

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1918021P08621Espacenet
EP 4641201 A22025-10-2922369P08621Espacenet
JP 2025517969 A2025-06-1222369P08621Espacenet
JP 2025517970 A2025-06-1218021P08621Espacenet
JP 2024509935 A2024-03-0534P08621Espacenet
US 11892452 B22024-02-0659P08621Espacenet
US 11860162 B22024-01-021068P08621Espacenet
JP 2023123507 A2023-09-0533P08621Espacenet
US 11694765 B22023-07-04326P08621Espacenet
US 11446398 B22022-09-2079924P08621Espacenet

1 to 10 of 61

See all 61 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,378

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSNRNP70 papersNewest fiscal year
ZIAES101074Environmental/genetic Risk Factors and Pathogenesis of Autoimmune Disease142025
P30CA008748Cancer Center Support Grant102025
P30AR070254Johns Hopkins Rheumatic Diseases Resource-based Core Center (Johns Hopkins RDRCC)82025
ZIAAR041203Muscle Disease Unit82025
R01DK058110Dose-Dependent Effects of Hormone on the Activity of Estrogen Receptor Enhancers and Target Genes72025
R01DK069710The Role of Nuclear PARPs in Signal-Regulated Transcription62025
R01HL034594RISK FACTORS FOR CVD IN WOMEN62025
T32AR048522Multidisciplinary Rheumatology Training Program62025
P30CA014051Cancer Center Support (Core) Grant52025
P30CA016672Cancer Center Support Grant52025

1 to 10 of 1,378Source NIH's project files

See all 1,378 nih grants

Papers2,902

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Widespread exon definition is promoted by the U1 snRNP 70K subunit and requires sites of contact with RNA Polymerase II.bioRxiv202642818336PubTator, text miningPubMed
The relationship between autoantibody and complement levels in the sera of patients with systemic lupus erythematosus.Clin Immunol202642790660PubTator, text miningPubMed
Prevalence and Clinical Associations of Systemic Sclerosis-Related Autoantibodies: A Nationwide Reuma.pt Cohort Study.Antibodies (Basel)202642776798PubTator, text miningPubMed
Utility of an extended 12-autoantibody panel in systemic sclerosis: Clinical and prognostic implications in a real-life cohort.Rev Clin Esp (Barc)202642772597PubTator, text miningPubMed
The association between cardiac arrhythmia and autoantibodies in systemic sclerosis.Mod Rheumatol202642757877PubTator, text miningPubMed
GPR56 and CD319 identify distinct cytotoxic-associated DP and DN T-cell subsets in early systemic lupus erythematosus.Clin Rheumatol202642745124PubTator, text miningPubMed
Cancer in Systemic Sclerosis: Clinical Associations and Prognostic Impact From the EUSTAR Registry.Arthritis Rheumatol202642663235PubTator, text miningPubMed
Wernicke's encephalopathy in mixed connective tissue disease triggered by persistent vomiting: a case report and literature review.Rheumatol Int202642550248PubTator, text miningPubMed
Fluorescence imaging-based investigation of tau-mediated promotion of U1 small nuclear ribonucleoprotein 70 kDa co-phase separation.Int J Biol Macromol202642526554PubTator, text miningPubMed
Evolution of Recurrent Myxofibrosarcoma of the Thoracic Wall at Single-Cell Resolution: A Case Report.Int J Mol Sci202642511573PubTator, text miningPubMed

1 to 10 of 2,902

See all 2,902 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6625

GET https://conductscience.org/api/genes/v1/6625/patents?page=2