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SOD2: superoxide dismutase 2

1 protein, 86 patents, 0 drugs, 0 trials, 8,086 NIH grants and 20,405 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSOD2HGNC
Namesuperoxide dismutase 2HGNC
NCBI Gene ID6648NCBI Gene
HGNC IDHGNC:11180HGNC
EnsemblENSG00000291237NCBI Gene
AliasesGC1, GClnc1, IPO-B, IPOB, MNSOD, MVCD6, Mn-SOD, MnSOD, lncRNA-GC1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P04179Superoxide dismutase [Mn], mitochondrial22248Ensembl, GeneID, HGNCUniProt

Patents 86

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4719461 A12026-04-08133P04179Espacenet
EP 4661917 A12025-12-1713P04179Espacenet
EP 4650780 A22025-11-198159P04179Espacenet
EP 4641201 A22025-10-298318P04179Espacenet
JP 2025517969 A2025-06-128318P04179Espacenet
JP 2025517970 A2025-06-128159P04179Espacenet
WO 2024252368 A22024-12-1220P04179Espacenet
US 11446398 B22022-09-2084982P04179Espacenet
US 11446398 B22022-09-2084991P04179Espacenet
US 11408034 B22022-08-09564P04179Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 8086

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA086862Cancer Center Support Grant612,025NIH's project files
P30CA016672Cancer Center Support Grant412,025NIH's project files
P30ES005605Environmental Health Sciences Research Center372,025NIH's project files
R01ES010563Mechanisms of Manganese Neurotoxicity342,025NIH's project files
P30CA177558University of Kentucky Markey Cancer Center – Cancer Center Support Grant282,025NIH's project files
P42ES013661Iowa Superfund Research Program: Airborne PCBs: Sources, Exposures, Toxicities, Remediation212,025NIH's project files
P30ES010126UNC Center for Environmental Health and Susceptibility202,025NIH's project files
P30CA036727Buffett Cancer Center Support Grant192,025NIH's project files
P30ES009089Center for Environmental Health in Northern Manhattan192,025NIH's project files
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant172,025NIH's project files

Papers 20405

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42824679PubTator, text miningPubMed
42812214PubTator, text miningPubMed
42809895PubTator, text miningPubMed
42805153PubTator, text miningPubMed
42800293PubTator, text miningPubMed
42795268PubTator, text miningPubMed
42792671PubTator, text miningPubMed
42792158PubTator, text miningPubMed
42785307PubTator, text miningPubMed
42774487PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license