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Gene · 6649

SOD3: superoxide dismutase 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SOD3: superoxide dismutase 3. Genes, record 6649. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6649

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Gene

Symbol
SOD3
HGNC
Name
superoxide dismutase 3
HGNC
NCBI Gene ID
6649
NCBI Gene
HGNC ID
HGNC:11181
HGNC
Ensembl
ENSG00000109610
NCBI Gene
Aliases
EC-SOD
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P08294Extracellular superoxide dismutase [Cu-Zn]2401Ensembl, GeneID, HGNC

Source UniProt

Patents45

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4719461 A12026-04-08229P08294Espacenet
EP 4650780 A22025-11-1910521P08294Espacenet
JP 2025147176 A2025-10-0612638P08294Espacenet
JP 2025529142 A2025-09-047766P08294Espacenet
US 12371689 B22025-07-297766P08294Espacenet
JP 2025517970 A2025-06-1210521P08294Espacenet
JP 2025032204 A2025-03-1136239P08294Espacenet
JP 2025028160 A2025-02-2812638P08294Espacenet
KR 1020250010750 A2025-01-2112638P08294Espacenet
KR 1020240176874 A2024-12-261P08294Espacenet

1 to 10 of 45

See all 45 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,947

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSOD3 papersNewest fiscal year
P30CA086862Cancer Center Support Grant142025
P30DK054759Precision Medicine Center for Cystic Fibrosis102025
P30ES001247Environmental Agents as Modulators of Disease Processes102025
P40OD010440Caenorhabditis Genetics Center92025
I01BX001232Cu importer CTR1 Cys189 oxidation in atherosclerosis82025
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant82025
P30ES005605Environmental Health Sciences Research Center82025
P30CA046934University of Colorado Cancer Center Support Grant62025
T32HL007171Translational Pulmonary Vascular Biology Program62025
P30CA177558University of Kentucky Markey Cancer Center – Cancer Center Support Grant52025

1 to 10 of 1,947Source NIH's project files

See all 1,947 nih grants

Papers3,288

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Identification of superoxide dismutase 3 as a critical factor for dermal stem cell maintenance.J Dermatol Sci202642701085PubTator, text miningPubMed
Transcriptomic Study of Mechanism Driving Conjunctival Fibrosis Following Glaucoma Filtration Surgery.Biomedicines202642652101PubTator, text miningPubMed
Molecular predictors of recurrence in vestibular schwannomas: a transcriptomic and RT-qPCR analysis.Eur Arch Otorhinolaryngol202642642532PubTator, text miningPubMed
Seed priming-mediated molecular responses enhance thermo-osmotic resilience in Halophila ovalis for climate-resilient restoration.J Environ Manage202642537253PubTator, text miningPubMed
Sex-Specific Association Between Serum SOD Activity and Osteoporosis in Type 2 Diabetes: A Cross-Sectional Study with Functional Validation.J Clin Med202642513515PubTator, text miningPubMed
Pivotal Factors in Breast Cancer Molecular Subtypes Apoptosis Induction by ELF-EMF; Ki-67, ROS Level, HER-2, and SODs.Breast J202642467070PubTator, text miningPubMed
Integrated molecular, microRNA, and biochemical profiling reveals oxidative stress-driven degeneration of the ligamentum flavum in lumbar spinal stenosis.Sci Rep202642236915PubTator, text miningPubMed
Exploring hypoxia-related genes as prognostic indicators in lung adenocarcinoma.PLoS One202642234659PubTator, text miningPubMed
Human biliary atresia extrahepatic cholangiocyte organoids express increased ER and oxidative stress, altered drug metabolism and cell polarity changes.Front Bioeng Biotechnol202642183052PubTator, text miningPubMed
Transcriptomic Evidence Reveals the IIS-FOXO-SOD2 Axis as a Core Anti-Aging Pathway in Long-Lived Queens of Odontotermes formosanus.Insects202642042474PubTator, text miningPubMed

1 to 10 of 3,288

See all 3,288 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6649

GET https://conductscience.org/api/genes/v1/6649/patents?page=2