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Gene · 665

BNIP3L: BCL2 interacting protein 3 like

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. BNIP3L: BCL2 interacting protein 3 like. Genes, record 665. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/665

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Gene

Symbol
BNIP3L
HGNC
Name
BCL2 interacting protein 3 like
HGNC
NCBI Gene ID
665
NCBI Gene
HGNC ID
HGNC:1085
HGNC
Ensembl
ENSG00000104765
NCBI Gene
Aliases
BNIP3a, NIP3L, NIX, Nix
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O60238BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like2190Ensembl, GeneID, HGNC

Source UniProt

Patents54

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1910343O60238Espacenet
EP 4641201 A22025-10-2910663O60238Espacenet
JP 2025529142 A2025-09-04592O60238Espacenet
US 12371689 B22025-07-29592O60238Espacenet
JP 2025517969 A2025-06-1210663O60238Espacenet
JP 2025517970 A2025-06-1210343O60238Espacenet
JP 2025062604 A2025-04-148548O60238Espacenet
JP 2024123008 A2024-09-105015O60238Espacenet
US 11666661 B22023-06-0615O60238Espacenet
US 11446398 B22022-09-208548O60238Espacenet

1 to 10 of 54

See all 54 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,586

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleBNIP3L papersNewest fiscal year
P30CA008748Cancer Center Support Grant102025
P30CA056036Translational Research in Cancer82025
ZIAAG000723ALZHEIMERS RESEARCH PROJECT: DNA repair dysfunction in neurodegeneration and Alzheimer's Disease82025
P20GM103427Nebraska Research Network in Functional Genomics62025
P30CA016672Cancer Center Support Grant62025
P30CA142543UT Southwestern Medical Center Simmons Comprehensive Cancer Center62025
R01AI100874The natural killer cell response against mouse cytomegalovirus infection62025
T32CA009594Multi-Disciplinary Training Grant in Cancer Research62025
P30CA006973Regional Oncology Research Center52025
R01CA200310BNIP3 and BNIP3L (NIX) in lipid homeostasis and growth control in the liver52025

1 to 10 of 1,586Source NIH's project files

See all 1,586 nih grants

Papers2,878

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A Bibliometric Review of Research Trends and Therapeutic Potential Reveals Natural Products as Major Regulators of Mitophagy in Kidney Disease.Mini Rev Med Chem202642817106PubTator, text miningPubMed
P INK1/PARKIN mitophagy: a potential regulator of mitochondrial homeostasis in functional dyspepsia.Front Physiol202642812598PubTator, text miningPubMed
Transcriptional Regulation of Receptor-Mediated Mitophagy in Sunitinib-Resistant Renal Cancer Cells: Response to Succinic Acid.Pharmaceuticals (Basel)202642797377PubTator, text miningPubMed
NIX-associated mitochondrial remodeling contributes to esophageal epithelial differentiation.bioRxiv202642779802PubTator, text miningPubMed
Linking HLA class II susceptibility to HSPC transcriptomics and antigen presentation in aplastic anemia.Front Immunol202642774213PubTator, text miningPubMed
Mitophagy-driven immune evasion in skin cancer: multidimensional regulatory networks and context-dependent therapeutic strategies-a narrative review.Front Immunol202642769533PubTator, text miningPubMed
Mitophagy in idiopathic pulmonary fibrosis: from molecular mechanisms to therapeutic opportunities.Front Cell Dev Biol202642769024PubTator, text miningPubMed
Effects of homozygous PARK7 gene mutations L166P and M26I on BNIP3/BNIP3L interactions and ER-mitochondria proximity.Biol Direct202642723107PubTator, text miningPubMed
Mitochondrial-centric regulatory networks in MASLD: Integrating quality control, organelle interactions, and gut-liver communication.Pharmacol Res202642628854PubTator, text miningPubMed
Urolithin A enhances mitochondrial biogenesis-related markers and maximal respiratory capacity during C2C12 differentiation.Front Cell Dev Biol202642453124PubTator, text miningPubMed

1 to 10 of 2,878

See all 2,878 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/665

GET https://conductscience.org/api/genes/v1/665/patents?page=2