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Gene · 6652

SORD: sorbitol dehydrogenase

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SORD: sorbitol dehydrogenase. Genes, record 6652. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6652

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Gene

Symbol
SORD
HGNC
Name
sorbitol dehydrogenase
HGNC
NCBI Gene ID
6652
NCBI Gene
HGNC ID
HGNC:11184
HGNC
Ensembl
ENSG00000140263
NCBI Gene
Aliases
HEL-S-95n, HMNR8, RDH, SDH, SORD1, SORDD, XDH
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q00796Sorbitol dehydrogenase3573Ensembl, GeneID, HGNC

Source UniProt

Patents22

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1464943Q00796Espacenet
EP 4641201 A22025-10-292213Q00796Espacenet
JP 2025114630 A2025-08-0546Q00796Espacenet
JP 2025517969 A2025-06-122213Q00796Espacenet
US 12083168 B22024-09-1046Q00796Espacenet
US 11446398 B22022-09-2082423Q00796Espacenet
JP 2022531466 A2022-07-06536Q00796Espacenet
JP 2022092366 A2022-06-22693Q00796Espacenet
JP 2022524081 A2022-04-27185394Q00796Espacenet
KR 1020220025713 A2022-03-0346Q00796Espacenet

1 to 10 of 22

See all 22 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants618

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSORD papersNewest fiscal year
P30DK048520Colorado Nutrition Obesity Research Center52025
P30CA051008Georgetown University Lombardi Comprehensive Cancer Center Support Grant42025
P30DK036836Diabetes Research Center32025
U01DK065184Michigan Hepatotoxicity Clinical Research Network Renewal32025
P30CA046934University of Colorado Cancer Center Support Grant22025
P50CA097186The Pacific Northwest Prostate Cancer SPORE22025
R01NS072248Genome Studies in Hereditary Spastic Paraplegia- Beyond the Exome22025
U01DK065176Drug Induced Liver Injury Network Data Coordinating Center22025
U01DK065201University of North Carolina Clinical Center for DILIN22025
U01DK065211IU Clinical Center: Drug Induced Liver Injury Network22025

1 to 10 of 618Source NIH's project files

See all 618 nih grants

Papers2,028

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
An Investigation to Study Morphology, Nanomechanical Attributes, Transcriptomics, and Proteomics of Tumor Associated Macrophages Derived Extracellular Vesicles in the Tumor Microenvironment.J Anal Oncol202642719843PubTator, text miningPubMed
Unexpected Conduction Blocks in SORD-Related Distal Motor Neuropathy: A Case Report.Clin Case Rep202642688681PubTator, text miningPubMed
A network toxicology and machine learning approach to uncover the molecular machinery of bisphenol A-induced colorectal cancer.Sci Rep202642624872PubTator, text miningPubMed
When muscles matter in SORD neuropathy.J Neuropathol Exp Neurol202642616755PubTator, text miningPubMed
Lactate dehydrogenase A exhibits sorbitol/fructose-related catalytic activity and contributes to polyol pathway metabolism in tumor cells.Front Endocrinol (Lausanne)202642548485PubTator, text miningPubMed
Metabolic reprogramming in polyol pathway contributes to anti-inflammatory effect of glucosamine salts on synovial fibroblasts.NPJ Metab Health Dis202642386885PubTator, text miningPubMed
Effects of trehalose, melatonin and lipid mixtures on bull sperm parameters and gene expressions during cryopreservation.Cryobiology202642269524PubTator, text miningPubMed
Correction to: Expanding the phenotype of SORD mutation.Brain202642228017PubTator, text miningPubMed
In-Depth Plasma Proteomics Identifies SNCA as a Discriminating Biomarker of PDAC.J Proteome Res202642223356PubTator, text miningPubMed
Integrated multi-omics data and machine learning approaches to decipher the molecular network and gene signatures of renal cell carcinoma induced by aristolochic acid.Biochem Biophys Res Commun202642033937PubTator, text miningPubMed

1 to 10 of 2,028

See all 2,028 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6652

GET https://conductscience.org/api/genes/v1/6652/patents?page=2