Gene · 6656
SOX1: SRY-box transcription factor 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. SOX1: SRY-box transcription factor 1. Genes, record 6656. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6656
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O00570 | Transcription factor SOX-1 | 391 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents38
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 65414 | O00570 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15650 | O00570 | Espacenet |
| JP 2025530805 A | 2025-09-17 | 4 | O00570 | Espacenet |
| KR 1020250068664 A | 2025-05-16 | 4 | O00570 | Espacenet |
| EP 4553154 A1 | 2025-05-14 | 14 | O00570 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15650 | O00570 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15650 | O00570 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 15489 | O00570 | Espacenet |
| US 12024722 B2 | 2024-07-02 | 168 | O00570 | Espacenet |
| US 11976296 B2 | 2024-05-07 | 12 | O00570 | Espacenet |
1 to 10 of 38
See all 38 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,617
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | SOX1 papers | Newest fiscal year |
|---|---|---|---|
| ZIATR000018 | Drug Repurposing Screening for Rare and Neglected Diseases | 8 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 7 | 2025 |
| ZICHL006145 | NHLBI iPSC Core Facility | 6 | 2025 |
| R01EY012200 | Pax6 as a key regulator of lens development | 5 | 2025 |
| R01NS126227 | Seronegative Autoimmune Encephalopathies: Biomarker Discovery, Validation & Deep Phenotyping | 5 | 2025 |
| P30CA014051 | Cancer Center Support (Core) Grant | 4 | 2025 |
| P30CA016042 | Cancer Center Support Grant | 4 | 2025 |
| P51OD011106 | Wisconsin National Primate Research Center Support | 4 | 2025 |
| K12HD001259 | UC San Diego Womens Reproductive Health Research Program | 3 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 3 | 2025 |
1 to 10 of 1,617Source NIH's project files
See all 1,617 nih grantsPapers2,883
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| SOX1 methylation predicts postoperative pathological downgrading in CIN3 lesions before biopsy. | Eur J Obstet Gynecol Reprod Biol | 2026 | 42822165 | PubTator, text mining | PubMed |
| Paraneoplastic Neurological Syndrome in a Patient with Limited-stage Small-cell Lung Cancer Receiving Durvalumab Maintenance after Concurrent Chemoradiotherapy: A Case Report. | Intern Med | 2026 | 42749652 | PubTator, text mining | PubMed |
| Prolonged Post-Electroconvulsive Therapy Delirium in Treatment-Resistant Depression With Central Nervous System Risk Factors Under Programmed Cell Death Protein 1 Inhibitor Therapy: A Case Report. | J ECT | 2026 | 42744285 | PubTator, text mining | PubMed |
| Diagnostic Accuracy of DNA Methylation Markers for Detecting Cervical Precancer and Cervical Cancer: A Systematic Review and Meta-analysis. | Arch Acad Emerg Med | 2026 | 42699011 | PubTator, text mining | PubMed |
| Sodium Butyrate-Assisted Induction of Posterior Pre-Neural Progenitors from Pluripotent Stem Cells. | Int J Mol Sci | 2026 | 42511848 | PubTator, text mining | PubMed |
| Case Report: A case of paraneoplastic autoimmune encephalitis with concurrent anti-GABABR and anti-SOX1 antibody positivity. | Front Cell Neurosci | 2026 | 42494433 | PubTator, text mining | PubMed |
| Loss of the lncRNA SOX1-OT promotes p53-dependent cell-cycle arrest in astrocytes. | bioRxiv | 2026 | 42427539 | PubTator, text mining | PubMed |
| Anti-VGCC negative and Anti-SOX1 positive Lambert-Eaton myasthenic syndrome as the initial presentation of small cell lung cancer: a case report. | Front Oncol | 2026 | 42388632 | PubTator, text mining | PubMed |
| Diagnostic value of FAM19A4/SOX1/PAX1 methylation in non-16/18 high-risk HPV cervical lesions. | Gynecol Oncol | 2026 | 42335608 | PubTator, text mining | PubMed |
| Integrated protocol for concurrent generation of microglial and neuronal cells in human cerebral organoids. | BMC Methods | 2026 | 42306776 | PubTator, text mining | PubMed |
1 to 10 of 2,883
See all 2,883 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/6656
GET https://conductscience.org/api/genes/v1/6656/patents?page=2