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Gene · 6656

SOX1: SRY-box transcription factor 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SOX1: SRY-box transcription factor 1. Genes, record 6656. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6656

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Gene

Symbol
SOX1
HGNC
Name
SRY-box transcription factor 1
HGNC
NCBI Gene ID
6656
NCBI Gene
HGNC ID
HGNC:11189
HGNC
Ensembl
ENSG00000182968
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O00570Transcription factor SOX-13910Ensembl, GeneID, HGNC

Source UniProt

Patents38

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1465414O00570Espacenet
JP 2025147176 A2025-10-0615650O00570Espacenet
JP 2025530805 A2025-09-174O00570Espacenet
KR 1020250068664 A2025-05-164O00570Espacenet
EP 4553154 A12025-05-1414O00570Espacenet
JP 2025028160 A2025-02-2815650O00570Espacenet
KR 1020250010750 A2025-01-2115650O00570Espacenet
JP 2024109657 A2024-08-1415489O00570Espacenet
US 12024722 B22024-07-02168O00570Espacenet
US 11976296 B22024-05-0712O00570Espacenet

1 to 10 of 38

See all 38 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,617

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSOX1 papersNewest fiscal year
ZIATR000018Drug Repurposing Screening for Rare and Neglected Diseases82025
P30CA008748Cancer Center Support Grant72025
ZICHL006145NHLBI iPSC Core Facility62025
R01EY012200Pax6 as a key regulator of lens development52025
R01NS126227Seronegative Autoimmune Encephalopathies: Biomarker Discovery, Validation & Deep Phenotyping52025
P30CA014051Cancer Center Support (Core) Grant42025
P30CA016042Cancer Center Support Grant42025
P51OD011106Wisconsin National Primate Research Center Support42025
K12HD001259UC San Diego Womens Reproductive Health Research Program32025
P30CA016672Cancer Center Support Grant32025

1 to 10 of 1,617Source NIH's project files

See all 1,617 nih grants

Papers2,883

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
SOX1 methylation predicts postoperative pathological downgrading in CIN3 lesions before biopsy.Eur J Obstet Gynecol Reprod Biol202642822165PubTator, text miningPubMed
Paraneoplastic Neurological Syndrome in a Patient with Limited-stage Small-cell Lung Cancer Receiving Durvalumab Maintenance after Concurrent Chemoradiotherapy: A Case Report.Intern Med202642749652PubTator, text miningPubMed
Prolonged Post-Electroconvulsive Therapy Delirium in Treatment-Resistant Depression With Central Nervous System Risk Factors Under Programmed Cell Death Protein 1 Inhibitor Therapy: A Case Report.J ECT202642744285PubTator, text miningPubMed
Diagnostic Accuracy of DNA Methylation Markers for Detecting Cervical Precancer and Cervical Cancer: A Systematic Review and Meta-analysis.Arch Acad Emerg Med202642699011PubTator, text miningPubMed
Sodium Butyrate-Assisted Induction of Posterior Pre-Neural Progenitors from Pluripotent Stem Cells.Int J Mol Sci202642511848PubTator, text miningPubMed
Case Report: A case of paraneoplastic autoimmune encephalitis with concurrent anti-GABABR and anti-SOX1 antibody positivity.Front Cell Neurosci202642494433PubTator, text miningPubMed
Loss of the lncRNA SOX1-OT promotes p53-dependent cell-cycle arrest in astrocytes.bioRxiv202642427539PubTator, text miningPubMed
Anti-VGCC negative and Anti-SOX1 positive Lambert-Eaton myasthenic syndrome as the initial presentation of small cell lung cancer: a case report.Front Oncol202642388632PubTator, text miningPubMed
Diagnostic value of FAM19A4/SOX1/PAX1 methylation in non-16/18 high-risk HPV cervical lesions.Gynecol Oncol202642335608PubTator, text miningPubMed
Integrated protocol for concurrent generation of microglial and neuronal cells in human cerebral organoids.BMC Methods202642306776PubTator, text miningPubMed

1 to 10 of 2,883

See all 2,883 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6656

GET https://conductscience.org/api/genes/v1/6656/patents?page=2