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SOX2: SRY-box transcription factor 2

1 protein, 359 patents, 0 drugs, 0 trials, 14,106 NIH grants and 36,341 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSOX2HGNC
NameSRY-box transcription factor 2HGNC
NCBI Gene ID6657NCBI Gene
HGNC IDHGNC:11195HGNC
EnsemblENSG00000181449NCBI Gene
AliasesANOP3, MCOPS3NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P48431Transcription factor SOX-231713Ensembl, GeneID, HGNCUniProt

Patents 359

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4810513 A12026-09-231P48431Espacenet
EP 4805378 A12026-09-16690P48431Espacenet
WO 2026171881 A12026-08-203P48431Espacenet
EP 4759932 A12026-06-173P48431Espacenet
JP 2026091847 A2026-06-044P48431Espacenet
JP 2026086827 A2026-05-264P48431Espacenet
EP 4733399 A12026-04-2924P48431Espacenet
EP 4705273 A22026-03-119P48431Espacenet
US 12559772 B22026-02-242P48431Espacenet
US 12540940 B22026-02-0331P48431Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 14106

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant1832,025NIH's project files
P30CA016672Cancer Center Support Grant1362,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award442,025NIH's project files
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-2028432,025NIH's project files
P30CA014195Cancer Center Support Grant (CCSG)422,025NIH's project files
P30CA060553The Robert H. Lurie Comprehensive Cancer Center362,025NIH's project files
R01HL113006Human Induced Pluripotent Stem Cells for Cardiovascular Disease Modeling362,025NIH's project files
P30CA036727Buffett Cancer Center Support Grant322,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant312,025NIH's project files
P30CA006973Regional Oncology Research Center302,025NIH's project files

Papers 36341

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42825038PubTator, text miningPubMed
42822446PubTator, text miningPubMed
42818793PubTator, text miningPubMed
42818440PubTator, text miningPubMed
42817679PubTator, text miningPubMed
42812127PubTator, text miningPubMed
42811996PubTator, text miningPubMed
42794654PubTator, text miningPubMed
42794641PubTator, text miningPubMed
42794548PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license