Gene · 6660
SOX5: SRY-box transcription factor 5
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. SOX5: SRY-box transcription factor 5. Genes, record 6660. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6660
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P35711 | Transcription factor SOX-5 | 763 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents39
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 65432 | P35711 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 14436 | P35711 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15664 | P35711 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 14436 | P35711 | Espacenet |
| JP 2025506185 A | 2025-03-07 | 51 | P35711 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15664 | P35711 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15664 | P35711 | Espacenet |
| EP 4479067 A2 | 2024-12-25 | 51 | P35711 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 15503 | P35711 | Espacenet |
| JP 2023544161 A | 2023-10-20 | 64 | P35711 | Espacenet |
1 to 10 of 39
See all 39 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,622
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | SOX5 papers | Newest fiscal year |
|---|---|---|---|
| P30DK063491 | Diabetes Research Center (DRC) | 6 | 2025 |
| R01HL092577 | IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVAL | 6 | 2025 |
| P30CA072720 | Cancer Center Support Grant | 4 | 2025 |
| U10AA008401 | Collaborative Study on the Genetics of Alcoholism (COGA). | 4 | 2025 |
| P30AR072572 | UW Core Center for Clinical Research of Musculoskeletal Conditions | 3 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 3 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 3 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 3 | 2025 |
| R01HL086694 | From GWAS loci to blood pressure genes, variants & mechanisms - Renewal | 3 | 2025 |
| R01MH123489 | Prediction of suicide death using EHR and polygenic risk scores | 3 | 2025 |
1 to 10 of 1,622Source NIH's project files
See all 1,622 nih grantsPapers1,923
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Shared genetic architecture across social disconnection, social disadvantage, and psychiatric and neurodevelopmental traits. | Eur Arch Psychiatry Clin Neurosci | 2026 | 42814113 | PubTator, text mining | PubMed |
| Genotype-dependent miR-499/SOX5 axis regulation and its association with chronic low back pain risk and severity. | J Orthop Surg Res | 2026 | 42750036 | PubTator, text mining | PubMed |
| A cascade-release microsphere-engineered injectable hydrogel enables immune remodeling and sustained chondrogenesis for facial cartilage regeneration. | J Mater Chem B | 2026 | 42727235 | PubTator, text mining | PubMed |
| Single-cell RNA sequencing reveals chondrocyte heterogeneity and fibrocartilage transition in osteonecrosis of the femoral head. | iScience | 2026 | 42668562 | PubTator, text mining | PubMed |
| CRISPR activation reveals SOX5/6/9 as key transcriptional regulators directing iPSC-derived cells toward a notochordal lineage. | Stem Cell Reports | 2026 | 42660118 | PubTator, text mining | PubMed |
| Effectiveness of cognitive training on Lamb-Shaffer syndrome: a case report. | Dement Neuropsychol | 2026 | 42657202 | PubTator, text mining | PubMed |
| Genetic Etiology and Neurodevelopmental Outcomes in Children With Craniosynostosis: A 15-Year Single-Center Retrospective Study. | J Craniofac Surg | 2026 | 42607197 | PubTator, text mining | PubMed |
| Retraction Notice to: Inhibition of TDP43-Mediated SNHG12-miR-195-SOX5 Feedback Loop Impeded Malignant Biological Behaviors of Glioma Cells. | Mol Ther Nucleic Acids | 2026 | 42542639 | PubTator, text mining | PubMed |
| Dysregulation of lncRNA MEG3/miR-21-5p Axis Impairs SOX5 Expression in Osteoarthritis. | Genes (Basel) | 2026 | 42510788 | PubTator, text mining | PubMed |
Retraction notice to "Circ_0084653 promotes the tumor progression and immune escape in triple-negative breast cancer via the deubiquitination of MYC and upregulation of SOX5" [International Journal of Biological Macromolecules 280 (2024) 135655]. | Int J Biol Macromol | 2026 | 42481325 | PubTator, text mining | PubMed |
1 to 10 of 1,923
See all 1,923 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/6660
GET https://conductscience.org/api/genes/v1/6660/patents?page=2