Gene · 6672
SP100: SP100 nuclear body protein
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. SP100: SP100 nuclear body protein. Genes, record 6672. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6672
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P23497 | Nuclear autoantigen Sp-100 | 879 | 122 | Ensembl, GeneID, HGNC |
Source UniProt
Patents50
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 64996 | P23497 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 2295 | P23497 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 1861 | P23497 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15671 | P23497 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 1861 | P23497 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 2295 | P23497 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15671 | P23497 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15671 | P23497 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 15510 | P23497 | Espacenet |
| JP 2023123507 A | 2023-09-05 | 105 | P23497 | Espacenet |
1 to 10 of 50
See all 50 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants948
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | SP100 papers | Newest fiscal year |
|---|---|---|---|
| P30CA010815 | Consolidated Basic Cancer Research Program | 23 | 2025 |
| ZIAAI000713 | Replication mechanisms of human papillomaviruses (HPV) | 7 | 2025 |
| T32CA009171 | Training Program in Basic Cancer Research | 6 | 2025 |
| R01DE017336 | Epigenetic Regulation of Epstein-Barr Virus | 5 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| R01CA117830 | Epigenomic Control of KSHV Latency | 4 | 2025 |
| R01CA140337 | Host pathways regulating Epstein-Barr virus-mediated B cell growth transformation | 3 | 2025 |
| P01AI127335 | Human Cytomegalovirus dysregulation of host hematopoietic progenitor cell signaling pathways to modulate latency and reactivation | 2 | 2025 |
| P01CA022443 | Molecular Biology and Genetics of Human Tumor Viruses | 2 | 2025 |
| P01CA049605 | Bone Marrow Grafting and Cellular Therapy for Leukemia and Lymphoma | 2 | 2025 |
1 to 10 of 948Source NIH's project files
See all 948 nih grantsPapers1,643
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Nuclear localization of the glutaminyl-tRNA synthetase QARS reveals its role in DNA damage response in ovarian cancer. | Nat Commun | 2026 | 42706241 | PubTator, text mining | PubMed |
| Time-resolved mapping in calves reveals bovine herpesvirus 1 shift from mucosal replication to trigeminal ganglion neuroinvasion with promyelocytic leukemia protein-centered host-virus antagonism. | Microbiol Spectr | 2026 | 42489478 | PubTator, text mining | PubMed |
| Epigenetic regulation of transgenes. | J Biotechnol | 2026 | 42214794 | PubTator, text mining | PubMed |
| Autoantibodies in the diagnostics, prognostics and follow-up of primary biliary cholangitis. | J Transl Autoimmun | 2026 | 41970282 | PubTator, text mining | PubMed |
| Validation of a Multiparametric, Automated, Macroarray-Based Assay for the Detection of Autoantibodies in Autoimmune Liver Disease. | J Clin Lab Anal | 2026 | 41951558 | PubTator, text mining | PubMed |
| Discovery of novel murine PML isoforms. | Nucleus | 2026 | 41871027 | PubTator, text mining | PubMed |
| Consensus statements of the Hellenic Autoimmune Liver Diseases Study Group on the diagnosis and current management of primary biliary cholangitis. | Ann Gastroenterol | 2026 | 41868880 | PubTator, text mining | PubMed |
| Dual Positivity for AMA/AMA-M2 and Anti-gp210/sp100 Shows Highest Diagnostic Value for Primary Biliary Cholangitis. | Aliment Pharmacol Ther | 2026 | 41845567 | PubTator, text mining | PubMed |
| An SP110-SP100 axis is a critical regulator of promyelocytic leukaemia body dynamics and mitotic fidelity. | Nat Cell Biol | 2026 | 41826696 | PubTator, text mining | PubMed |
| Fatigue and circadian rhythm in non-cirrhotic primary biliary cholangitis: An exploratory comparison with primary sclerosing cholangitis and healthy controls. | World J Hepatol | 2026 | 41809483 | PubTator, text mining | PubMed |
1 to 10 of 1,643
See all 1,643 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/6672
GET https://conductscience.org/api/genes/v1/6672/patents?page=2