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Gene · 6672

SP100: SP100 nuclear body protein

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SP100: SP100 nuclear body protein. Genes, record 6672. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6672

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Gene

Symbol
SP100
HGNC
Name
SP100 nuclear body protein
HGNC
NCBI Gene ID
6672
NCBI Gene
HGNC ID
HGNC:11206
HGNC
Ensembl
ENSG00000067066
NCBI Gene
Aliases
lysp100b
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P23497Nuclear autoantigen Sp-100879122Ensembl, GeneID, HGNC

Source UniProt

Patents50

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1464996P23497Espacenet
EP 4650780 A22025-11-192295P23497Espacenet
EP 4641201 A22025-10-291861P23497Espacenet
JP 2025147176 A2025-10-0615671P23497Espacenet
JP 2025517969 A2025-06-121861P23497Espacenet
JP 2025517970 A2025-06-122295P23497Espacenet
JP 2025028160 A2025-02-2815671P23497Espacenet
KR 1020250010750 A2025-01-2115671P23497Espacenet
JP 2024109657 A2024-08-1415510P23497Espacenet
JP 2023123507 A2023-09-05105P23497Espacenet

1 to 10 of 50

See all 50 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants948

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSP100 papersNewest fiscal year
P30CA010815Consolidated Basic Cancer Research Program232025
ZIAAI000713Replication mechanisms of human papillomaviruses (HPV)72025
T32CA009171Training Program in Basic Cancer Research62025
R01DE017336Epigenetic Regulation of Epstein-Barr Virus52025
P30CA008748Cancer Center Support Grant42025
R01CA117830Epigenomic Control of KSHV Latency42025
R01CA140337Host pathways regulating Epstein-Barr virus-mediated B cell growth transformation32025
P01AI127335Human Cytomegalovirus dysregulation of host hematopoietic progenitor cell signaling pathways to modulate latency and reactivation22025
P01CA022443Molecular Biology and Genetics of Human Tumor Viruses22025
P01CA049605Bone Marrow Grafting and Cellular Therapy for Leukemia and Lymphoma22025

1 to 10 of 948Source NIH's project files

See all 948 nih grants

Papers1,643

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Nuclear localization of the glutaminyl-tRNA synthetase QARS reveals its role in DNA damage response in ovarian cancer.Nat Commun202642706241PubTator, text miningPubMed
Time-resolved mapping in calves reveals bovine herpesvirus 1 shift from mucosal replication to trigeminal ganglion neuroinvasion with promyelocytic leukemia protein-centered host-virus antagonism.Microbiol Spectr202642489478PubTator, text miningPubMed
Epigenetic regulation of transgenes.J Biotechnol202642214794PubTator, text miningPubMed
Autoantibodies in the diagnostics, prognostics and follow-up of primary biliary cholangitis.J Transl Autoimmun202641970282PubTator, text miningPubMed
Validation of a Multiparametric, Automated, Macroarray-Based Assay for the Detection of Autoantibodies in Autoimmune Liver Disease.J Clin Lab Anal202641951558PubTator, text miningPubMed
Discovery of novel murine PML isoforms.Nucleus202641871027PubTator, text miningPubMed
Consensus statements of the Hellenic Autoimmune Liver Diseases Study Group on the diagnosis and current management of primary biliary cholangitis.Ann Gastroenterol202641868880PubTator, text miningPubMed
Dual Positivity for AMA/AMA-M2 and Anti-gp210/sp100 Shows Highest Diagnostic Value for Primary Biliary Cholangitis.Aliment Pharmacol Ther202641845567PubTator, text miningPubMed
An SP110-SP100 axis is a critical regulator of promyelocytic leukaemia body dynamics and mitotic fidelity.Nat Cell Biol202641826696PubTator, text miningPubMed
Fatigue and circadian rhythm in non-cirrhotic primary biliary cholangitis: An exploratory comparison with primary sclerosing cholangitis and healthy controls.World J Hepatol202641809483PubTator, text miningPubMed

1 to 10 of 1,643

See all 1,643 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6672

GET https://conductscience.org/api/genes/v1/6672/patents?page=2