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SPARC: secreted protein acidic and cysteine rich

1 protein, 140 patents, 0 drugs, 0 trials, 3,816 NIH grants and 7,155 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSPARCHGNC
Namesecreted protein acidic and cysteine richHGNC
NCBI Gene ID6678NCBI Gene
HGNC IDHGNC:11219HGNC
EnsemblENSG00000113140NCBI Gene
AliasesBM-40, OI17, ON, ONTNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P09486SPARC3034Ensembl, GeneID, HGNCUniProt

Patents 140

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
WO 2026215134 A12026-10-156P09486Espacenet
EP 4650780 A22025-11-19789P09486Espacenet
EP 4640849 A22025-10-2996P09486Espacenet
EP 4641201 A22025-10-29558P09486Espacenet
JP 2025147176 A2025-10-0612676P09486Espacenet
JP 2025529142 A2025-09-047777P09486Espacenet
US 12371689 B22025-07-297777P09486Espacenet
JP 2025519096 A2025-06-2496P09486Espacenet
JP 2025517969 A2025-06-12558P09486Espacenet
JP 2025517970 A2025-06-12789P09486Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3816

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant282,025NIH's project files
P30CA008748Cancer Center Support Grant192,025NIH's project files
P30CA006973Regional Oncology Research Center112,025NIH's project files
P30EY010572Ophthalmology Core Facility102,025NIH's project files
R01HL076246Chemokines in healing myocardial infarction102,025NIH's project files
R01HL085440Resolution of inflammation in healing myocardial infarcts102,025NIH's project files
P30CA016058Cancer Center Support Grant92,025NIH's project files
P30CA091842Cancer Center Support Grant92,025NIH's project files
P30CA060553The Robert H. Lurie Comprehensive Cancer Center82,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award82,025NIH's project files

Papers 7155

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42826565PubTator, text miningPubMed
42823844PubTator, text miningPubMed
42820806PubTator, text miningPubMed
42814897PubTator, text miningPubMed
42804136PubTator, text miningPubMed
42804094PubTator, text miningPubMed
42799068PubTator, text miningPubMed
42787770PubTator, text miningPubMed
42785820PubTator, text miningPubMed
42775789PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license