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Gene · 6708

SPTA1: spectrin alpha, erythrocytic 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SPTA1: spectrin alpha, erythrocytic 1. Genes, record 6708. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6708

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Gene

Symbol
SPTA1
HGNC
Name
spectrin alpha, erythrocytic 1
HGNC
NCBI Gene ID
6708
NCBI Gene
HGNC ID
HGNC:11272
HGNC
Ensembl
ENSG00000163554
NCBI Gene
Aliases
EL2, HPP, HS3, SPH3, SPTA
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P02549Spectrin alpha chain, erythrocytic 12,4193Ensembl, GeneID, HGNC

Source UniProt

Patents20

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
US 12560619 B22026-02-2484P02549Espacenet
JP 2026004568 A2026-01-1465094P02549Espacenet
EP 4641201 A22025-10-2924900P02549Espacenet
JP 2025517969 A2025-06-1224900P02549Espacenet
US 12038446 B22024-07-1684P02549Espacenet
US 11446398 B22022-09-2082900P02549Espacenet
JP 2022524081 A2022-04-27185871P02549Espacenet
US 11078247 B22021-08-0310936P02549Espacenet
WO 2020043864 A12020-03-052457P02549Espacenet
JP 2019054813 A2019-04-11245529P02549Espacenet

1 to 10 of 20

See all 20 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,200

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSPTA1 papersNewest fiscal year
ZIADK031117Development of Drugs Acting at Adenosine Receptors222025
ZIADK031126Computer Modeling of G Protein-Coupled Receptors202025
ZIADK031115Functionalized Congeners of Bioactive Compounds112025
ZIADK031116Development of P2Y Receptor Ligands92025
P30CA008748Cancer Center Support Grant82025
P30CA010815Consolidated Basic Cancer Research Program82025
P30CA016672Cancer Center Support Grant62025
P30DK063491Diabetes Research Center (DRC)62025
ZIADA000606Structural basis for the functions of dopamine receptors, neurotransmitter transporters, and sigma 1 receptor62025
R01HL146442The role of ferroptosis in red cell aging in vivo and in vitro52025

1 to 10 of 1,200Source NIH's project files

See all 1,200 nih grants

Papers1,813

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Severe Hereditary Pyropoikilocytosis/Hereditary Elliptocytosis-Like Phenotype Associated With a Heterozygous SPTA1 Variant in a Cambodian Girl: A Case Report.Case Rep Hematol202642801053PubTator, text miningPubMed
Proximal Seal After Endovascular Aneurysm Repair: Why Sealing Length Dynamics and Type 2 Endoleak Matter.J Endovasc Ther202642411058PubTator, text miningPubMed
Plasma proteome differences between giant cell arteritis and polymyalgia rheumatica: a pilot study.Arthritis Res Ther202642387612PubTator, text miningPubMed
Statistical association of complete PYHIN gene family loss with flight and inverted roosting in bats.Front Immunol202642292384PubTator, text miningPubMed
Hereditary Spherocytosis: A Case Series Spanning Prenatal Detection to Neonatal Care.Prenat Diagn202642175794PubTator, text miningPubMed
Oxidative refolding and NMR analysis of the second extracellular loop of human Occludin: The C216-C237 disulfide bond as a structural linchpin.Protein Expr Purif202642167388PubTator, text miningPubMed
Expanding the genetic spectrum of hereditary spherocytosis: novel mutations and phenotypic heterogeneity from a 55-patient cohort.Ann Hematol202642126446PubTator, text miningPubMed
"The Road Less Traveled": Endovascular Embolization of a Type II Endoleak via Corona Mortis.Diagnostics (Basel)202642072819PubTator, text miningPubMed
Clinicohematological and Genetic Profile of Hereditary Spherocytosis in Children: An Experience From a North Indian Center.J Pediatr Hematol Oncol202642054241PubTator, text miningPubMed
Molecular characteristics of proximal and distal esophagogastric junction adenocarcinoma.J Thorac Dis202641988313PubTator, text miningPubMed

1 to 10 of 1,813

See all 1,813 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6708

GET https://conductscience.org/api/genes/v1/6708/patents