Gene · 6708
SPTA1: spectrin alpha, erythrocytic 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. SPTA1: spectrin alpha, erythrocytic 1. Genes, record 6708. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6708
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P02549 | Spectrin alpha chain, erythrocytic 1 | 2,419 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents20
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| US 12560619 B2 | 2026-02-24 | 84 | P02549 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 65094 | P02549 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 24900 | P02549 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 24900 | P02549 | Espacenet |
| US 12038446 B2 | 2024-07-16 | 84 | P02549 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 82900 | P02549 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 185871 | P02549 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 10936 | P02549 | Espacenet |
| WO 2020043864 A1 | 2020-03-05 | 2457 | P02549 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 245529 | P02549 | Espacenet |
1 to 10 of 20
See all 20 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,200
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | SPTA1 papers | Newest fiscal year |
|---|---|---|---|
| ZIADK031117 | Development of Drugs Acting at Adenosine Receptors | 22 | 2025 |
| ZIADK031126 | Computer Modeling of G Protein-Coupled Receptors | 20 | 2025 |
| ZIADK031115 | Functionalized Congeners of Bioactive Compounds | 11 | 2025 |
| ZIADK031116 | Development of P2Y Receptor Ligands | 9 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 8 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 8 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 6 | 2025 |
| ZIADA000606 | Structural basis for the functions of dopamine receptors, neurotransmitter transporters, and sigma 1 receptor | 6 | 2025 |
| R01HL146442 | The role of ferroptosis in red cell aging in vivo and in vitro | 5 | 2025 |
1 to 10 of 1,200Source NIH's project files
See all 1,200 nih grantsPapers1,813
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Severe Hereditary Pyropoikilocytosis/Hereditary Elliptocytosis-Like Phenotype Associated With a Heterozygous SPTA1 Variant in a Cambodian Girl: A Case Report. | Case Rep Hematol | 2026 | 42801053 | PubTator, text mining | PubMed |
| Proximal Seal After Endovascular Aneurysm Repair: Why Sealing Length Dynamics and Type 2 Endoleak Matter. | J Endovasc Ther | 2026 | 42411058 | PubTator, text mining | PubMed |
| Plasma proteome differences between giant cell arteritis and polymyalgia rheumatica: a pilot study. | Arthritis Res Ther | 2026 | 42387612 | PubTator, text mining | PubMed |
| Statistical association of complete PYHIN gene family loss with flight and inverted roosting in bats. | Front Immunol | 2026 | 42292384 | PubTator, text mining | PubMed |
| Hereditary Spherocytosis: A Case Series Spanning Prenatal Detection to Neonatal Care. | Prenat Diagn | 2026 | 42175794 | PubTator, text mining | PubMed |
| Oxidative refolding and NMR analysis of the second extracellular loop of human Occludin: The C216-C237 disulfide bond as a structural linchpin. | Protein Expr Purif | 2026 | 42167388 | PubTator, text mining | PubMed |
| Expanding the genetic spectrum of hereditary spherocytosis: novel mutations and phenotypic heterogeneity from a 55-patient cohort. | Ann Hematol | 2026 | 42126446 | PubTator, text mining | PubMed |
| "The Road Less Traveled": Endovascular Embolization of a Type II Endoleak via Corona Mortis. | Diagnostics (Basel) | 2026 | 42072819 | PubTator, text mining | PubMed |
| Clinicohematological and Genetic Profile of Hereditary Spherocytosis in Children: An Experience From a North Indian Center. | J Pediatr Hematol Oncol | 2026 | 42054241 | PubTator, text mining | PubMed |
| Molecular characteristics of proximal and distal esophagogastric junction adenocarcinoma. | J Thorac Dis | 2026 | 41988313 | PubTator, text mining | PubMed |
1 to 10 of 1,813
See all 1,813 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/6708
GET https://conductscience.org/api/genes/v1/6708/patents