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Gene · 6709

SPTAN1: spectrin alpha, non-erythrocytic 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SPTAN1: spectrin alpha, non-erythrocytic 1. Genes, record 6709. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6709

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Gene

Symbol
SPTAN1
HGNC
Name
spectrin alpha, non-erythrocytic 1
HGNC
NCBI Gene ID
6709
NCBI Gene
HGNC ID
HGNC:11273
HGNC
Ensembl
ENSG00000197694
NCBI Gene
Aliases
DEE5, DEVEP, EIEE5, HMN11, HMND11, NEAS, SPG91, SPTA2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q13813Spectrin alpha chain, non-erythrocytic 12,4727Ensembl, GeneID, HGNC

Source UniProt

Patents25

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1465098Q13813Espacenet
EP 4650780 A22025-11-199160Q13813Espacenet
EP 4641201 A22025-10-299410Q13813Espacenet
JP 2025517969 A2025-06-129410Q13813Espacenet
JP 2025517970 A2025-06-129160Q13813Espacenet
JP 2023064789 A2023-05-1288Q13813Espacenet
WO 2023074712 A2023-05-0434Q13813Espacenet
JP 2022141755 A2022-09-29736Q13813Espacenet
US 11446398 B22022-09-2082904Q13813Espacenet
JP 2022524081 A2022-04-27185875Q13813Espacenet

1 to 10 of 25

See all 25 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,199

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSPTAN1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant42025
P30CA021765Cancer Center Support Grant (CCSG)42025
U54GM104938Oklahoma Shared Clinical and Translational Resources42025
R01NS094003Axonal Pathology and TBI-Related Neurodegeneration (TReND)32025
IK2RX003651Traumatic and Treatable Vascular Pathology in the Outcome of TBI22025
P30CA013330Cancer Center Support Grant22025
P30CA016086Cancer Center Support Grant22025
P30CA016672Cancer Center Support Grant22025
P30CA022453CANCER CENTER SUPPORT GRANT22025
P30CA054174Mays Cancer Center at UT Health SA22025

1 to 10 of 1,199Source NIH's project files

See all 1,199 nih grants

Papers1,635

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Functional Characterization of RNA Profiles in Processing Bodies of Embryonic Stem Cells and Mesodermal Cells.Genomics Proteomics Bioinformatics202642671352PubTator, text miningPubMed
Antisense oligonucleotides treatment uncovers differences in the modulation of dysregulated intracellular pathways in Spinal Muscular Atrophy motoneurons.Cell Death Dis202642443163PubTator, text miningPubMed
Elucidating the Role of SET as a Key Contributor to Neurodevelopmental Disability Within the 9q34.11 Deletion Syndrome Interval.Clin Genet202642432431PubTator, text miningPubMed
A Dose-Response Study on Human FGF21 to Inhibit Necrosis, Spectrin Breakdown, and to Increase Intracellular Cold Shock Proteins in Cultured Cortical Neurons Subjected to Oxygen-Glucose Deprivation Injury.
Mol Neurobiol202642387004PubTator, text miningPubMed
Role of Spatial Heterogeneity in Muscle-Invasive Bladder Cancer on Overall Survival and Immunotherapy Response.Cancers (Basel)202641827808PubTator, text miningPubMed
Non-Conventional and Emerging Autoantibodies in Sjögren's Disease.J Inflamm Res202641798638PubTator, text miningPubMed
Targeting Expanded CUG and CTG Repeats as a Therapeutic Approach for Myotonic Dystrophy Type 1 (DM1).ChemMedChem202641797662PubTator, text miningPubMed
Neurodegeneration Biomarkers in Epilepsy: A Critical Review of Current Findings.Life (Basel)202641752932PubTator, text miningPubMed
Molecular Profiling of Polish Pediatric Patients with Epilepsy: A Single-Center Diagnostic Experience Using Next-Generation Sequencing.Genes (Basel)202641751517PubTator, text miningPubMed
Deciphering the Impact of RAC1-SPTAN1 in ARPKD Cystogenesis Using Multifaceted Models.Adv Sci (Weinh)202641742835PubTator, text miningPubMed

1 to 10 of 1,635

See all 1,635 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6709

GET https://conductscience.org/api/genes/v1/6709/patents?page=2