Gene · 671
BPI: bactericidal permeability increasing protein
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. BPI: bactericidal permeability increasing protein. Genes, record 671. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/671
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P17213 | Bactericidal permeability-increasing protein | 487 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents51
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| US 12509511 B2 | 2025-12-30 | 8 | P17213 | Espacenet |
| JP 2025169942 A | 2025-11-14 | 872 | P17213 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 1536 | P17213 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 596 | P17213 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 5602 | P17213 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 5602 | P17213 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 596 | P17213 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 8164 | P17213 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 1536 | P17213 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 1536 | P17213 | Espacenet |
1 to 10 of 51
See all 51 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants767
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | BPI papers | Newest fiscal year |
|---|---|---|---|
| P30ES005605 | Environmental Health Sciences Research Center | 9 | 2025 |
| T32AI007046 | Infectious Diseases Training Program | 6 | 2025 |
| ZIAHD002400 | The Role Of Subclinical Infection And Cytokines In Preterm Parturition | 4 | 2025 |
| P30CA023108 | Cancer Center Support Grant | 3 | 2025 |
| U19AI057229 | Understanding Influenza and SARS-CoV-2 vaccine responses, in vivo and in vitro | 3 | 2025 |
| K12HD047349 | Pediatric Critical Care and Trauma Scientist Development Program (PCCTSDP) | 2 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 2 | 2025 |
| P30DA018343 | Yale/NIDA Neuroproteomics Center | 2 | 2025 |
| P30DK017047 | Diabetes Research Center | 2 | 2025 |
| P30DK065988 | UNC Cystic Fibrosis Research and Translation Core Center | 2 | 2025 |
1 to 10 of 767Source NIH's project files
See all 767 nih grantsPapers1,446
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Augmented Anti-Bactericidal Permeability-Increasing Protein Antibody Levels in Rheumatoid Arthritis Patients Complicated by Usual Interstitial Pneumonia. | J Clin Med | 2026 | 42513347 | PubTator, text mining | PubMed |
| Therapeutic Efficacy of Sivelestat Sodium in ARDS Following Aortic Dissection: A Pilot Physiological Trial with Exploratory Transcriptomic Analysis. | J Inflamm Res | 2026 | 42502580 | PubTator, text mining | PubMed |
| Lipopolysaccharide-binding protein as a biomarker in the diagnosis of necrotizing enterocolitis. | J Pediatr Surg | 2026 | 42203141 | PubTator, text mining | PubMed |
| Pediatric ANCA-Associated Vasculitis: Variable Clinical Course in a Case Series of Three Patients and Literature Review. | Children (Basel) | 2026 | 42194238 | PubTator, text mining | PubMed |
Characterization of Mucosal BPI fold-containing family A member 1-High-Expressing Neutrophils and their Immune Defense roles in Severe Acute Respiratory Syndrome Coronavirus 2 Breakthrough Infection via single-cell RNA sequencing. | J Infect Dis | 2026 | 42139518 | PubTator, text mining | PubMed |
| Identification of neutrophil-related genes associated with the severity of RSV infection. | Microbiol Spectr | 2026 | 41995316 | PubTator, text mining | PubMed |
| From Gut to Systemic Circulation: Molecular Strategies of Botulinum Neurotoxin Complexes. | Toxins (Basel) | 2026 | 41893539 | PubTator, text mining | PubMed |
| GRN and KLRB1 define a shared peripheral-blood transcriptomic signature linking SLE and IPF. | J Transl Autoimmun | 2026 | 41782635 | PubTator, text mining | PubMed |
| Ontogenesis of coelomocyte subsets and immune-related genes during Eisenia andrei embryogenesis. | Dev Comp Immunol | 2026 | 41763506 | PubTator, text mining | PubMed |
| Dynamic Covalent Platform for Chiroptically Tunable Figure-Eight Macrocycles from Preorganized Alkaloidal Scaffolds. | JACS Au | 2026 | 41755847 | PubTator, text mining | PubMed |
1 to 10 of 1,446
See all 1,446 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/671
GET https://conductscience.org/api/genes/v1/671/patents?page=2