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Gene · 6710

SPTB: spectrin beta, erythrocytic

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SPTB: spectrin beta, erythrocytic. Genes, record 6710. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6710

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Gene

Symbol
SPTB
HGNC
Name
spectrin beta, erythrocytic
HGNC
NCBI Gene ID
6710
NCBI Gene
HGNC ID
HGNC:11274
HGNC
Ensembl
ENSG00000070182
NCBI Gene
Aliases
EL3, HS2, HSPTB1, SPH2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P11277Spectrin beta chain, erythrocytic2,1376Ensembl, GeneID, HGNC

Source UniProt

Patents22

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1465102P11277Espacenet
JP 2026004568 A2026-01-1465105P11277Espacenet
EP 4641201 A22025-10-2911119P11277Espacenet
JP 2025517969 A2025-06-1211119P11277Espacenet
JP 2025032204 A2025-03-1136462P11277Espacenet
EP 4461818 A22024-11-1336462P11277Espacenet
JP 2023058610 A2023-04-2536462P11277Espacenet
US 11446398 B22022-09-2082911P11277Espacenet
JP 2022524081 A2022-04-27185882P11277Espacenet
US 11078247 B22021-08-0310938P11277Espacenet

1 to 10 of 22

See all 22 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,071

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSPTB papersNewest fiscal year
ZIADK031117Development of Drugs Acting at Adenosine Receptors82025
ZIADK031115Functionalized Congeners of Bioactive Compounds72025
ZIADK031126Computer Modeling of G Protein-Coupled Receptors72025
P30CA010815Consolidated Basic Cancer Research Program62025
R01DK050107Transcriptional Control of Hemoglobin Synthesis and Erythrocyte Development52025
R01DK111430Molecular Analysis of Transcriptional Enhancers in Hematopoiesis42025
UL1TR001863Yale Clinical and Translational Science Award42025
ZIADK031116Development of P2Y Receptor Ligands42025
R01DK103794Systematic Genetic Dissection of Human Erythropoiesis32025
U54DK106829Stem Cell and Transplantation Biology32025

1 to 10 of 1,071Source NIH's project files

See all 1,071 nih grants

Papers1,578

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Clinical characteristics, genotype-phenotype correlation, and prognostic follow-up of 48 Chinese children with hereditary spherocytosis.Front Med (Lausanne)202642819045PubTator, text miningPubMed
Case Report: A research on a case of hereditary spherocytosis with idiopathic pulmonary hemosiderosis.Front Pediatr202642558654PubTator, text miningPubMed
Decoding the Ektacytometric Landscape of Hereditary Spherocytosis: Insights from 204 Cases.Diagnostics (Basel)202642510120PubTator, text miningPubMed
Identification of a novel hereditary spherocytosis gene mutation in a Chinese child with α-globin gene triplication.MedScience202642467362PubTator, text miningPubMed
High-efficiency 14-plex cSNP SNaPshot assay for forensic peripheral blood identification.BMC Genomics202642436368PubTator, text miningPubMed
Screening of hereditary elliptocytosis caused by SPTB mutations and identification of its association with significant jaundice among Thai neonates.BMJ Paediatr Open202642379836PubTator, text miningPubMed
Hereditary Hemolytic Spherocytosis in the Active-Duty Population: A Unique Case.Cureus202642326196PubTator, text miningPubMed
Hereditary Spherocytosis: A Case Series Spanning Prenatal Detection to Neonatal Care.Prenat Diagn202642175794PubTator, text miningPubMed
Expanding the genetic spectrum of hereditary spherocytosis: novel mutations and phenotypic heterogeneity from a 55-patient cohort.Ann Hematol202642126446PubTator, text miningPubMed
Predictive functional profiling of 16S rRNA genes amplicons reveals bioremediation and sulfur metabolism capacity in thermophilic hot spring bacteriomes.Sci Rep202642086823PubTator, text miningPubMed

1 to 10 of 1,578

See all 1,578 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6710

GET https://conductscience.org/api/genes/v1/6710/patents?page=2