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BRCA1: BRCA1 DNA repair associated

1 protein, 186 patents, 0 drugs, 0 trials, 16,208 NIH grants and 65,310 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolBRCA1HGNC
NameBRCA1 DNA repair associatedHGNC
NCBI Gene ID672NCBI Gene
HGNC IDHGNC:1100HGNC
EnsemblENSG00000012048NCBI Gene
AliasesBRCAI, BRCC1, BROVCA1, FANCS, IRIS, PNCA4, PPP1R53, PSCP, RNF53NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P38398Breast cancer type 1 susceptibility protein1,86333Ensembl, GeneID, HGNCUniProt

Patents 186

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4641201 A22025-10-297434P38398Espacenet
EP 4641202 A22025-10-295270P38398Espacenet
JP 2025147176 A2025-10-0614811P38398Espacenet
JP 2025147176 A2025-10-0616581P38398Espacenet
JP 2025108697 A2025-07-238P38398Espacenet
JP 2025517969 A2025-06-127434P38398Espacenet
JP 2025074818 A2025-05-146P38398Espacenet
JP 2025062604 A2025-04-149555P38398Espacenet
WO 2025059215 A12025-03-201P38398Espacenet
JP 2025028160 A2025-02-2814811P38398Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 16208

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant8842,025NIH's project files
P30CA016672Cancer Center Support Grant6912,025NIH's project files
P50CA116201Mayo Clinic Breast Cancer SPORE2162,025NIH's project files
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant1602,025NIH's project files
P30CA006973Regional Oncology Research Center1562,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant1542,025NIH's project files
P50CA136393Use of microfluidic tumor cultures to enable clinical trials of therapies for ovarian cancer1442,025NIH's project files
P30CA051008Georgetown University Lombardi Comprehensive Cancer Center Support Grant1352,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase1332,025NIH's project files
P30CA016058Cancer Center Support Grant1162,025NIH's project files

Papers 65310

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42826577PubTator, text miningPubMed
42826492PubTator, text miningPubMed
42822083PubTator, text miningPubMed
42821448PubTator, text miningPubMed
42818548PubTator, text miningPubMed
42818478PubTator, text miningPubMed
42818459PubTator, text miningPubMed
42818163PubTator, text miningPubMed
42817725PubTator, text miningPubMed
42812597PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license