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SREBF1: sterol regulatory element binding transcription factor 1

1 protein, 61 patents, 0 drugs, 0 trials, 5,690 NIH grants and 14,402 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSREBF1HGNC
Namesterol regulatory element binding transcription factor 1HGNC
NCBI Gene ID6720NCBI Gene
HGNC IDHGNC:11289HGNC
EnsemblENSG00000072310NCBI Gene
AliasesHMD, IFAP2, SREBP-1c, SREBP1, SREBP1a, bHLHd1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P36956Sterol regulatory element-binding protein 11,1471Ensembl, GeneID, HGNCUniProt

Patents 61

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-191929P36956Espacenet
EP 4641201 A22025-10-291517P36956Espacenet
JP 2025147176 A2025-10-0615688P36956Espacenet
JP 2025529142 A2025-09-044445P36956Espacenet
JP 2025121934 A2025-08-206P36956Espacenet
US 12371689 B22025-07-294445P36956Espacenet
JP 2025517969 A2025-06-121517P36956Espacenet
JP 2025517970 A2025-06-121929P36956Espacenet
JP 2025062601 A2025-04-1466P36956Espacenet
JP 2025028160 A2025-02-2815688P36956Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 5690

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30DK020572Michigan Diabetes Research Center (MDRC)282,025NIH's project files
P30CA016672Cancer Center Support Grant252,025NIH's project files
P30DK026743UCSF Liver Center252,025NIH's project files
P30DK056341Washington University Nutrition Obesity Research Center232,025NIH's project files
P30DK048520Colorado Nutrition Obesity Research Center222,025NIH's project files
P30DK063491Diabetes Research Center (DRC)212,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award212,025NIH's project files
P01CA120964Molecular Pathogenesis of the Hamartoma Syndromes202,025NIH's project files
P30DK045735Yale Diabetes Research Center192,025NIH's project files
P50AA011999Southern California Research Center for ALPD and Cirrhosis192,025NIH's project files

Papers 14402

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42817800PubTator, text miningPubMed
42811544PubTator, text miningPubMed
42809056PubTator, text miningPubMed
42798608PubTator, text miningPubMed
42798489PubTator, text miningPubMed
42797439PubTator, text miningPubMed
42795589PubTator, text miningPubMed
42793239PubTator, text miningPubMed
42777924PubTator, text miningPubMed
42777652PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license