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Gene · 6749

SSRP1: structure specific recognition protein 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SSRP1: structure specific recognition protein 1. Genes, record 6749. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6749

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Gene

Symbol
SSRP1
HGNC
Name
structure specific recognition protein 1
HGNC
NCBI Gene ID
6749
NCBI Gene
HGNC ID
HGNC:11327
HGNC
Ensembl
ENSG00000149136
NCBI Gene
Aliases
FACT, FACT80, T160
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q08945FACT complex subunit SSRP170911Ensembl, GeneID, HGNC

Source UniProt

Patents36

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1465697Q08945Espacenet
EP 4650780 A22025-11-193019Q08945Espacenet
JP 2025147176 A2025-10-0615692Q08945Espacenet
JP 2025517970 A2025-06-123019Q08945Espacenet
JP 2025028160 A2025-02-2815692Q08945Espacenet
KR 1020250010750 A2025-01-2115692Q08945Espacenet
JP 2024109657 A2024-08-1415531Q08945Espacenet
JP 2024009871 A2024-01-2392Q08945Espacenet
JP 2023123507 A2023-09-0577Q08945Espacenet
US 11446398 B22022-09-2084722Q08945Espacenet

1 to 10 of 36

See all 36 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants921

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSSRP1 papersNewest fiscal year
P30CA016056Roswell Park Cancer Center Support Grant132025
P30CA008748Cancer Center Support Grant52025
P30CA016058Cancer Center Support Grant42025
P30CA016672Cancer Center Support Grant42025
P30CA021765Cancer Center Support Grant (CCSG)42025
P40OD010440Caenorhabditis Genetics Center42025
R01AI030612Virus-cell interactions affecting HSV gene expression42025
P30AG028740University of Florida Older Americans Independence Center (OAIC)32025
P30CA016087Cancer Center Support Grant32025
R01AG011085Ubiquitin‐mediated proteolysis and cell cycle control32025

1 to 10 of 921Source NIH's project files

See all 921 nih grants

Papers1,280

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
JP-1302 inhibits RNA polymerase I transcription and induces nucleolar stress in cancer cell lines.Cell Death Discov202642816485PubTator, text miningPubMed
HMGB2 Impacts Cisplatin-Induced DNA Adduct Processing in Chemoresistant Ovarian Cancer Cells.Genes (Basel)202642650109PubTator, text miningPubMed
Potential Relationship Between Ferroptosis and Pyroptosis in Myocardial Ischemia/Reperfusion Injury: Molecular Mechanisms and Therapeutic Targets.Rev Cardiovasc Med202642534140PubTator, text miningPubMed
Bioinformatics-driven discovery and experimental validation of differentially expressed genes in colorectal adenomas.Mol Biol Rep202642517945PubTator, text miningPubMed
The vesicular stomatitis virus matrix protein promotes FACT subunit depletion to suppress the FEAR pathway.PLoS Pathog202642467709PubTator, text miningPubMed
E3 Ligases and Deubiquitinases in Controlling High-Mobility Group Box (HMGB) Protein Functions.Int J Mol Sci202642353302PubTator, text miningPubMed
Multiomics Analysis Identifies Chromosomal Instability-Associated Immune-Related Signatures in Hepatocellular Carcinoma by Integrating Weighted Gene Coexpression Network Analysis (WGCNA) and Machine Learning.
Hum Mutat202642016321PubTator, text miningPubMed
Role of Bioinformatics in Identifying Novel Biomarkers for Immune Cell Exhaustion and Tumor Microenvironment.Technol Cancer Res Treat202641919636PubTator, text miningPubMed
The transcription elongation factors Spt4 and Spt6 promote dermal adipocyte differentiation.Adipocyte202641891546PubTator, text miningPubMed
A cell cycle-dependent transition of acetylation to phosphorylation regulates timely centrosome maturation.Nat Commun202641862458PubTator, text miningPubMed

1 to 10 of 1,280

See all 1,280 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6749

GET https://conductscience.org/api/genes/v1/6749/patents?page=2