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BRCA2: BRCA2 DNA repair associated

1 protein, 52 patents, 0 drugs, 0 trials, 10,091 NIH grants and 37,255 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolBRCA2HGNC
NameBRCA2 DNA repair associatedHGNC
NCBI Gene ID675NCBI Gene
HGNC IDHGNC:1101HGNC
EnsemblENSG00000139618NCBI Gene
AliasesBRCC2, BROVCA2, FACD, FAD, FAD1, FANCD, FANCD1, GLM3, PNCA2, XRCC11NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P51587Breast cancer type 2 susceptibility protein3,41814Ensembl, GeneID, HGNCUniProt

Patents 52

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1910274P51587Espacenet
EP 4640849 A22025-10-291553P51587Espacenet
EP 4641201 A22025-10-2910587P51587Espacenet
JP 2025519096 A2025-06-241553P51587Espacenet
JP 2025517969 A2025-06-1210587P51587Espacenet
JP 2025517970 A2025-06-1210274P51587Espacenet
JP 2025074818 A2025-05-148P51587Espacenet
JP 2025062604 A2025-04-149581P51587Espacenet
JP 2025062604 A2025-04-149584P51587Espacenet
EP 4464338 A22024-11-20160P51587Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 10091

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant6562,025NIH's project files
P30CA016672Cancer Center Support Grant4322,025NIH's project files
P50CA116201Mayo Clinic Breast Cancer SPORE1952,025NIH's project files
P30CA006973Regional Oncology Research Center1532,025NIH's project files
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant1252,025NIH's project files
P50CA136393Use of microfluidic tumor cultures to enable clinical trials of therapies for ovarian cancer1222,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase1022,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant972,025NIH's project files
P01CA092584Structural Cell Biology of DNA Repair Machines942,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant922,025NIH's project files

Papers 37255

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42824212PubTator, text miningPubMed
42823579PubTator, text miningPubMed
42822083PubTator, text miningPubMed
42818478PubTator, text miningPubMed
42817725PubTator, text miningPubMed
42812039PubTator, text miningPubMed
42811745PubTator, text miningPubMed
42810557PubTator, text miningPubMed
42809807PubTator, text miningPubMed
42807233PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license