Gene · 6753
SSTR3: somatostatin receptor 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. SSTR3: somatostatin receptor 3. Genes, record 6753. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6753
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P32745 | Somatostatin receptor type 3 | 418 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents50
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 64915 | P32745 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 64916 | P32745 | Espacenet |
| JP 2025172069 A | 2025-11-20 | 660 | P32745 | Espacenet |
| JP 2025172069 A | 2025-11-20 | 661 | P32745 | Espacenet |
| US 12247982 B2 | 2025-03-11 | 660 | P32745 | Espacenet |
| US 12247982 B2 | 2025-03-11 | 661 | P32745 | Espacenet |
| JP 2023113918 A | 2023-08-16 | 660 | P32745 | Espacenet |
| JP 2023113918 A | 2023-08-16 | 661 | P32745 | Espacenet |
| US 11541119 B2 | 2023-01-03 | 12 | P32745 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 82334 | P32745 | Espacenet |
1 to 10 of 50
See all 50 patentsDrugs9
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action | Source |
|---|---|---|---|---|
| LUTETIUM OXODOTREOTIDE | CHEMBL4302409 | Somatostatin receptor binding agent | BINDING AGENT | ChEMBL |
| LUTETIUM OXODOTREOTIDE LU-177 | CHEMBL4297545 | Somatostatin receptor binding agent | BINDING AGENT | ChEMBL |
| OCTREOTIDE | CHEMBL1680 | Somatostatin receptor agonist | AGONIST | ChEMBL |
| OCTREOTIDE ACETATE | CHEMBL1200480 | Somatostatin receptor agonist | AGONIST | ChEMBL |
| PASIREOTIDE | CHEMBL3349607 | Somatostatin receptor 3 agonist | AGONIST | ChEMBL |
| PASIREOTIDE DIASPARTATE | CHEMBL5314380 | Somatostatin receptor 3 agonist | AGONIST | ChEMBL |
| PASIREOTIDE PAMOATE | CHEMBL5314382 | Somatostatin receptor 3 agonist | AGONIST | ChEMBL |
| SOMATOSTATIN | CHEMBL1823872 | Somatostatin receptor agonist | AGONIST | ChEMBL |
| VAPREOTIDE | CHEMBL3349523 | Somatostatin receptor 3 agonist | AGONIST | ChEMBL |
Trials335
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT07595237 | LUTETIUM OXODOTREOTIDE LU-177 | EARLY_PHASE1 | ClinicalTrials.gov | |
| NCT07583563 | OCTREOTIDE | ClinicalTrials.gov | ||
| NCT07537010 | LUTETIUM OXODOTREOTIDE LU-177 | PHASE1 | ClinicalTrials.gov | |
| NCT07534371 | SOMATOSTATIN | ClinicalTrials.gov | ||
| NCT07460908 | OCTREOTIDE | ClinicalTrials.gov | ||
| NCT07316686 | LUTETIUM OXODOTREOTIDE LU-177 | PHASE1 | ClinicalTrials.gov | |
| NCT07304466 | SOMATOSTATIN | ClinicalTrials.gov | ||
| NCT07252401 | SOMATOSTATIN | ClinicalTrials.gov | ||
| NCT07229768 | LUTETIUM OXODOTREOTIDE LU-177 | EARLY_PHASE1 | ClinicalTrials.gov | |
| NCT07189871 | LUTETIUM OXODOTREOTIDE LU-177 | PHASE1/PHASE2 | ClinicalTrials.gov |
1 to 10 of 335
See all 335 trialsNIH grants509
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | SSTR3 papers | Newest fiscal year |
|---|---|---|---|
| R01GM089933 | Quality Control of the cilia proteome | 11 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| P30DK084567 | Mayo Center for Cell Signaling in Gastroenterology | 6 | 2025 |
| R01GM060992 | Intraflagellar Transport Proteins in Mice | 6 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
| P30DK020579 | Diabetes Research Center | 4 | 2025 |
| ZIACP010121 | Molecular Epidemiology Studies of Occupational and Environmental Exposures | 4 | 2025 |
| P30CA086862 | Cancer Center Support Grant | 3 | 2025 |
| R35GM122552 | Super-resolution Microscopy Study of Molecular Transport Mechanisms | 3 | 2025 |
| P30CA013148 | Comprehensive Cancer Center Support Grant | 2 | 2025 |
1 to 10 of 509Source NIH's project files
See all 509 nih grantsPapers1,165
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Predictors of in vitro response to somatostatin and dopamine receptor-targeted treatments are lacking in clinically non-functioning pituitary tumors. | J Neuroendocrinol | 2026 | 42785810 | PubTator, text mining | PubMed |
| Primary Cilia as Integrative Hubs of Metabolic Signaling in Type 2 Diabetes: Inter-Organ Evidence From Central, Peripheral, and Pancreatic Islet Tissues. | J Cell Physiol | 2026 | 42436646 | PubTator, text mining | PubMed |
| Primary cilia and neural computation. | J Biomed Sci | 2026 | 42231312 | PubTator, text mining | PubMed |
| Functional profiling of somatostatin receptors identifies somatostatin receptor subtype 2 as a vulnerability in Succinate Dehydrogenase SDHB-deficient pheochromocytomas and paragangliomas. | Mol Biomed | 2026 | 41928014 | PubTator, text mining | PubMed |
| Targeted and Personalized Therapy for Difficult Benign Brain Tumors: A Review. | J Pers Med | 2026 | 41893038 | PubTator, text mining | PubMed |
| Distinct molecular pathways leading to dosage-dependent temozolomide resistance in GBM stem cells. | Cancer Cell Int | 2026 | 41736030 | PubTator, text mining | PubMed |
| Structural and dynamic insights into ligand recognition and activation of somatostatin receptor 3. | Acta Pharmacol Sin | 2026 | 41673456 | PubTator, text mining | PubMed |
| Distribution of Somatostatin and Its Receptors in the Intestinal Tract in Healthy Patients and Patients with Type 2 Diabetes. | J Clin Endocrinol Metab | 2026 | 41379811 | PubTator, text mining | PubMed |
| Altered somatostatin receptor 3 expression and functional dysregulation in tuberous sclerosis complex. | Prog Neurobiol | 2026 | 41352576 | PubTator, text mining | PubMed |
| Clinical and Pathological Spectrum of Acromegaly: Distinguishing GH PitNETs, Mammosomatotrophs, and Mixed Tumors. | J Clin Endocrinol Metab | 2026 | 41296644 | PubTator, text mining | PubMed |
1 to 10 of 1,165
See all 1,165 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/6753
GET https://conductscience.org/api/genes/v1/6753/patents?page=2