ConductScience.org, home

Gene · 676

BRDT: bromodomain testis associated

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. BRDT: bromodomain testis associated. Genes, record 676. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/676

On this page

Gene

Symbol
BRDT
HGNC
Name
bromodomain testis associated
HGNC
NCBI Gene ID
676
NCBI Gene
HGNC ID
HGNC:1105
HGNC
Ensembl
ENSG00000137948
NCBI Gene
Aliases
BRD6, BRDt, CT9, SPGF21
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q58F21Bromodomain testis-specific protein94721Ensembl, GeneID, HGNC

Source UniProt

Patents50

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1439250Q58F21Espacenet
JP 2026004568 A2026-01-1439252Q58F21Espacenet
JP 2026004568 A2026-01-1439253Q58F21Espacenet
WO 2025243001 A12025-11-274Q58F21Espacenet
EP 4641201 A22025-10-297992Q58F21Espacenet
JP 2025517969 A2025-06-127992Q58F21Espacenet
JP 2025062604 A2025-04-149889Q58F21Espacenet
JP 2025062604 A2025-04-149892Q58F21Espacenet
EP 4487869 A22025-01-08116Q58F21Espacenet
JP 2024097033 A2024-07-17165Q58F21Espacenet

1 to 10 of 50

See all 50 patents

Drugs6

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
APABETALONECHEMBL2393130Bromodomain and extra-terminal motif (BET) inhibitorINHIBITORChEMBL
BIRABRESIBCHEMBL3581647Bromodomain and extra-terminal motif (BET) inhibitorINHIBITORChEMBL
EZOBRESIBCHEMBL4297458Bromodomain and extra-terminal motif (BET) inhibitorINHIBITORChEMBL
MOLIBRESIBCHEMBL1232461Bromodomain and extra-terminal motif (BET) inhibitorINHIBITORChEMBL
PELABRESIBCHEMBL4303404Bromodomain and extra-terminal motif (BET) inhibitorINHIBITORChEMBL
RO-6870810CHEMBL4297423Bromodomain and extra-terminal motif (BET) inhibitorINHIBITORChEMBL

Trials42

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07357727PELABRESIBPHASE3ClinicalTrials.gov
NCT07340138PELABRESIBPHASE1ClinicalTrials.gov
NCT06590324APABETALONEPHASE2/PHASE3ClinicalTrials.gov
NCT06401356PELABRESIBPHASE3ClinicalTrials.gov
NCT05372354EZOBRESIBPHASE1/PHASE2ClinicalTrials.gov
NCT04915300APABETALONEPHASE2ClinicalTrials.gov
NCT04894266APABETALONEPHASE2/PHASE3ClinicalTrials.gov
NCT04817007EZOBRESIBPHASE1/PHASE2ClinicalTrials.gov
NCT04603495PELABRESIBPHASE32024-10-28ClinicalTrials.gov
NCT03936465EZOBRESIBPHASE1ClinicalTrials.gov

1 to 10 of 42

See all 42 trials

NIH grants1,094

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleBRDT papersNewest fiscal year
P30CA076292Moffitt Cancer Center Support Grant102025
P30CA016672Cancer Center Support Grant82025
P30CA008748Cancer Center Support Grant72025
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202872025
P01CA066996Development of Novel Therapeutic Strategies in Human Leukemias62025
P50CA186786Michigan Prostate SPORE 2025-203062025
P30CA021765Cancer Center Support Grant (CCSG)52025
R01CA124633Pathogenesis and Treatment of NUT midline carcinoma52025
R35GM140837Chemical Probe Development for Epigenetic Complexes Enabled by Protein-Observed 19F NMR52025
P30AI027763UCSF-Bay Area Center for AIDS Research42025

1 to 10 of 1,094Source NIH's project files

See all 1,094 nih grants

Papers1,261

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
MAPK signaling links BRD2 chromatin occupancy to PI3K/AKT inhibitor sensitivity.bioRxiv202642818240PubTator, text miningPubMed
Integrative Analysis Identified an Eight-Gene Risk Signature Linked to CDK7 and Explored Its Association with HCC Progression via RelA Phosphorylation.Oncol Res202642500561PubTator, text miningPubMed
BRD4: From molecular understanding to therapeutics development.Mol Cell202642492506PubTator, text miningPubMed
Unraveling the layers of epigenetic control in respiratory antiviral defense.J Virol202642159289PubTator, text miningPubMed
Proximity Binding Assay for PROTAC Ternary Complex Analysis.ACS Sens202642011828PubTator, text miningPubMed
Meiotic prophase I disruption as a strategy for nonhormonal male contraception using small-molecule inhibitor JQ1.Proc Natl Acad Sci U S A202641945432PubTator, text miningPubMed
The histone acylation network: emerging therapeutic targets for remodeling the epigenetic landscape in pancreatic ductal adenocarcinoma.Cell Oncol (Dordr)202641874858PubTator, text miningPubMed
Clonal dynamics of HIV-infected and uninfected T cells.EBioMedicine202641855971PubTator, text miningPubMed
Quinoxaline Derivatives in Cancer Therapy: Insights into Mechanisms of Action and Therapeutic Applications.Biomol Ther (Seoul)202641755772PubTator, text miningPubMed
Redox-Genomic Crosstalk: Linking Oxidative Stress, Sperm DNA Fragmentation, and Epigenetics in Personalized Management of Male Infertility.J Pers Med202641745372PubTator, text miningPubMed

1 to 10 of 1,261

See all 1,261 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/676

GET https://conductscience.org/api/genes/v1/676/patents?page=2