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Gene · 6760

SS18: SS18 subunit of BAF chromatin remodeling complex

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SS18: SS18 subunit of BAF chromatin remodeling complex. Genes, record 6760. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6760

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Gene

Symbol
SS18
HGNC
Name
SS18 subunit of BAF chromatin remodeling complex
HGNC
NCBI Gene ID
6760
NCBI Gene
HGNC ID
HGNC:11340
HGNC
Ensembl
ENSG00000141380
NCBI Gene
Aliases
SMARCL1, SSXT, SYT
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q15532Protein SSXT4181Ensembl, GeneID, HGNC

Source UniProt

Patents17

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1466172Q15532Espacenet
EP 4650780 A22025-11-1913893Q15532Espacenet
JP 2025164846 A2025-10-3018Q15532Espacenet
JP 2025517970 A2025-06-1213893Q15532Espacenet
US 11446398 B22022-09-2085887Q15532Espacenet
WO 2022138944 A2022-06-3034Q15532Espacenet
JP 2022524081 A2022-04-27188858Q15532Espacenet
US 11078247 B22021-08-0311002Q15532Espacenet
WO 2021132592 A2021-07-0171Q15532Espacenet
JP 2019054813 A2019-04-11246607Q15532Espacenet

1 to 10 of 17

See all 17 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants759

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSS18 papersNewest fiscal year
P30CA008748Cancer Center Support Grant412025
P50CA217694SPORE in Soft Tissue Sarcoma162025
P30CA016672Cancer Center Support Grant92025
R01CA163915ATP-Dependent Chromatin Remodeling in Human Malignancy92025
P30CA042014Cancer Center Support Grant82025
P30CA068485Cancer Center Support Grant82025
P30CA021765Cancer Center Support Grant (CCSG)62025
P30EY008126Core Grant in Vision Research52025
P01CA066996Development of Novel Therapeutic Strategies in Human Leukemias42025
P30DK058404Molecular and Cellular Basis for Digestive Diseases42025

1 to 10 of 759Source NIH's project files

See all 759 nih grants

Papers1,411

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Diagnostic Utility of SS18-SSX Fusion-Specific and SSX C-Terminus Antibodies in Synovial Sarcoma: Validation in a Large Indian Tertiary Care Cohort.Appl Immunohistochem Mol Morphol202642820281PubTator, text miningPubMed
A Rare Case of Poorly Differentiated Synovial Sarcoma of the Superficial Neck: Diagnostic Approach in a Fine-Needle Aspiration Specimen.Diagn Cytopathol202642808294PubTator, text miningPubMed
When rare becomes real: diagnostic challenges and use of a multidisciplinary team-based decision in primary pulmonary synovial sarcoma.BMJ Case Rep202642608070PubTator, text miningPubMed
Primary pulmonary artery synovial sarcoma: a case report.AME Case Rep202642592483PubTator, text miningPubMed
Primary ovarian synovial sarcoma in an adolescent mimicking a germ cell tumor: A case report and diagnostic challenge.Gynecol Oncol Rep202642555456PubTator, text miningPubMed
[Clinical analysis of 9 children of B-cell acute lymphoblastic leukemia with MEF2D gene rearrangement].Zhonghua Er Ke Za Zhi202642527140PubTator, text miningPubMed
Plantar synovial sarcoma mimicking a vascular malformation in a child: a clinicopathologic case report.Int Cancer Conf J202642491187PubTator, text miningPubMed
Driver vs. passenger: Primary resistance to larotrectinib in synovial sarcoma harboring concurrent SS18 rearrangement and PDE3A-NTRK2 fusion.Tumori202642376758PubTator, text miningPubMed
Primary renal synovial sarcoma: a clinicopathological study of 23 cases highlighting the diagnostic value of SS18-SSX, TLE1, and INI1 immunohistochemistry panel.Virchows Arch202642371005PubTator, text miningPubMed
SMARCB1-Deficient Malignant Orbital Neoplasm with Features Overlapping Myxoid Epithelioid Sarcoma: A Diagnostic Challenge.Head Neck Pathol202642340513PubTator, text miningPubMed

1 to 10 of 1,411

See all 1,411 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6760

GET https://conductscience.org/api/genes/v1/6760/patents