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STAT1: signal transducer and activator of transcription 1

1 protein, 127 patents, 0 drugs, 0 trials, 15,715 NIH grants and 35,016 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSTAT1HGNC
Namesignal transducer and activator of transcription 1HGNC
NCBI Gene ID6772NCBI Gene
HGNC IDHGNC:11362HGNC
EnsemblENSG00000115415NCBI Gene
AliasesCANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT91NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P42224Signal transducer and activator of transcription 1-alpha/beta75010Ensembl, GeneID, HGNCUniProt

Patents 127

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
US 12539325 B22026-02-0370P42224Espacenet
EP 4641201 A22025-10-297954P42224Espacenet
EP 4641202 A22025-10-295332P42224Espacenet
WO 2025210091 A12025-10-097P42224Espacenet
JP 2025147176 A2025-10-0615694P42224Espacenet
JP 2025517969 A2025-06-127954P42224Espacenet
EP 4541373 A12025-04-231P42224Espacenet
JP 2025028160 A2025-02-2815694P42224Espacenet
KR 1020250017231 A2025-02-045332P42224Espacenet
KR 1020250010750 A2025-01-2115694P42224Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 15715

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant1362,025NIH's project files
P30CA008748Cancer Center Support Grant1072,025NIH's project files
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success782,025NIH's project files
P30CA016058Cancer Center Support Grant622,025NIH's project files
ZIAAI000647Genes And Gene Products As Immunoadjuvants572,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant502,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award492,025NIH's project files
R01AI127564Genome-wide search for inborn errors of IL-17 immunity underlying chronic mucocutaneous candidiasis382,025NIH's project files
P30CA091842Cancer Center Support Grant372,025NIH's project files
R01AR046713Cytokine regulation of RA synoviocyte phenotype372,025NIH's project files

Papers 35016

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42826657PubTator, text miningPubMed
42824448PubTator, text miningPubMed
42823185PubTator, text miningPubMed
42820287PubTator, text miningPubMed
42819011PubTator, text miningPubMed
42818784PubTator, text miningPubMed
42817167PubTator, text miningPubMed
42816648PubTator, text miningPubMed
42814769PubTator, text miningPubMed
42814515PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license