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STAT4: signal transducer and activator of transcription 4

1 protein, 67 patents, 0 drugs, 0 trials, 4,110 NIH grants and 6,821 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSTAT4HGNC
Namesignal transducer and activator of transcription 4HGNC
NCBI Gene ID6775NCBI Gene
HGNC IDHGNC:11365HGNC
EnsemblENSG00000138378NCBI Gene
AliasesDPMC, SLEB11NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q14765Signal transducer and activator of transcription 47480Ensembl, GeneID, HGNCUniProt

Patents 67

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4641201 A22025-10-297560Q14765Espacenet
JP 2025147176 A2025-10-0615697Q14765Espacenet
JP 2025517969 A2025-06-127560Q14765Espacenet
JP 2025028160 A2025-02-2815697Q14765Espacenet
KR 1020250010750 A2025-01-2115697Q14765Espacenet
JP 2024123008 A2024-09-108414Q14765Espacenet
JP 2024123008 A2024-09-108415Q14765Espacenet
JP 2024109657 A2024-08-1415536Q14765Espacenet
US 11944645 B22024-04-0253Q14765Espacenet
US 11701379 B22023-07-18194Q14765Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4110

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
ZIAAR041159Cytokine Signaling, Immunoregulation and Autoimmune and Immunodeficiency Diseases352,025NIH's project files
P30CA008748Cancer Center Support Grant292,025NIH's project files
P30CA016672Cancer Center Support Grant262,025NIH's project files
R01AI024717Genetic Linkage in Lupus222,025NIH's project files
R01AI100874The natural killer cell response against mouse cytomegalovirus infection222,025NIH's project files
U54GM104938Oklahoma Shared Clinical and Translational Resources152,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award152,025NIH's project files
R01AR063759Defining the influence of RA genetic susceptibility factors on T cell antigen specificity and functional state142,025NIH's project files
ZICAR041181Translational Immunology research: a support for clinical immunological research142,025NIH's project files
P01AI039671Costimulatory Mechanisms of Autoimmunity132,025NIH's project files

Papers 6821

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42824708PubTator, text miningPubMed
42812170PubTator, text miningPubMed
42778929PubTator, text miningPubMed
42748633PubTator, text miningPubMed
42697828PubTator, text miningPubMed
42686775PubTator, text miningPubMed
42658340PubTator, text miningPubMed
42653451PubTator, text miningPubMed
42653386PubTator, text miningPubMed
42603412PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license