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STAT6: signal transducer and activator of transcription 6

1 protein, 91 patents, 0 drugs, 0 trials, 5,631 NIH grants and 11,668 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSTAT6HGNC
Namesignal transducer and activator of transcription 6HGNC
NCBI Gene ID6778NCBI Gene
HGNC IDHGNC:11368HGNC
EnsemblENSG00000166888NCBI Gene
AliasesD12S1644, HIES6, IL-4-STAT, STAT6B, STAT6CNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P42226Signal transducer and activator of transcription 68477Ensembl, GeneID, HGNCUniProt

Patents 91

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1463576P42226Espacenet
JP 2026004568 A2026-01-1463577P42226Espacenet
JP 2026004568 A2026-01-1463583P42226Espacenet
JP 2026004568 A2026-01-1463590P42226Espacenet
EP 4650780 A22025-11-193986P42226Espacenet
EP 4641201 A22025-10-293568P42226Espacenet
EP 4627086 A22025-10-082P42226Espacenet
JP 2025147176 A2025-10-0615701P42226Espacenet
EP 4572801 A12025-06-2512P42226Espacenet
EP 4572802 A12025-06-2512P42226Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 5631

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant612,025NIH's project files
P30CA016672Cancer Center Support Grant532,025NIH's project files
U19AI070235Epithelial Genes in Allergic Inflammation322,025NIH's project files
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease302,025NIH's project files
ZIAAR041159Cytokine Signaling, Immunoregulation and Autoimmune and Immunodeficiency Diseases212,025NIH's project files
P50CA217694SPORE in Soft Tissue Sarcoma172,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)162,025NIH's project files
R01AI057459Allergic inflammation and Transcriptional Regulation in Th9 cells142,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award132,025NIH's project files
P30CA016058Cancer Center Support Grant122,025NIH's project files

Papers 11668

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42824278PubTator, text miningPubMed
42816943PubTator, text miningPubMed
42816545PubTator, text miningPubMed
42801147PubTator, text miningPubMed
42785223PubTator, text miningPubMed
42781455PubTator, text miningPubMed
42779462PubTator, text miningPubMed
42774082PubTator, text miningPubMed
42773249PubTator, text miningPubMed
42771093PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license