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Gene · 6781

STC1: stanniocalcin 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. STC1: stanniocalcin 1. Genes, record 6781. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6781

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Gene

Symbol
STC1
HGNC
Name
stanniocalcin 1
HGNC
NCBI Gene ID
6781
NCBI Gene
HGNC ID
HGNC:11373
HGNC
Ensembl
ENSG00000159167
NCBI Gene
Aliases
STC
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P52823Stanniocalcin-12470Ensembl, GeneID, HGNC

Source UniProt

Patents89

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1465497P52823Espacenet
EP 4650780 A22025-11-193421P52823Espacenet
JP 2025147176 A2025-10-0612917P52823Espacenet
JP 2025529142 A2025-09-047825P52823Espacenet
US 12371689 B22025-07-297825P52823Espacenet
JP 2025109968 A2025-07-251P52823Espacenet
JP 2025517970 A2025-06-123421P52823Espacenet
JP 2025028160 A2025-02-2812917P52823Espacenet
KR 1020250010750 A2025-01-2112917P52823Espacenet
JP 2024112982 A2024-08-214372P52823Espacenet

1 to 10 of 89

See all 89 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,191

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSTC1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant62025
P30CA016672Cancer Center Support Grant52025
P30CA068485Cancer Center Support Grant52025
R01HL086694From GWAS loci to blood pressure genes, variants & mechanisms - Renewal42025
I01BX002006Megalin, and transition from AKI to CKD32025
P30CA006973Regional Oncology Research Center32025
P30CA021765Cancer Center Support Grant (CCSG)32025
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202832025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant32025
P30DK063491Diabetes Research Center (DRC)32025

1 to 10 of 1,191Source NIH's project files

See all 1,191 nih grants

Papers1,853

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
STC1 is associated with tumor progression and suppressive niches in laryngeal squamous cell carcinoma.Transl Cancer Res202642724726PubTator, text miningPubMed
STC1 promotes osteogenic differentiation and represses inflammation via inhibition of NF‑κB signaling in mesenchymal stromal cells.Mol Med Rep202642563690PubTator, text miningPubMed
The ISL1-WDR5-H3K4me3-STC1 axis attenuates cerebral ischemia-reperfusion injury.Int Immunopharmacol202642497659PubTator, text miningPubMed
Correction: STC1 promotes colorectal cancer invasion and migration by regulating M2 macrophage polarization via TGF-β1/Smad signaling pathway.Front Med (Lausanne)202642494460PubTator, text miningPubMed
Size in small-for-gestational-age neonates correlates with insulin-like growth factor-binding protein proteolysis and insulin-like growth factor-I bioavailability.J Endocr Soc202642491477PubTator, text miningPubMed
Stanniocalcin 1 promotes gastric cancer progression by activating the PI3K/AKT pathway and inducing M2 macrophage polarization via the JAK2/STAT3/lL-10 axis.Chin Med J (Engl)202642484012PubTator, text miningPubMed
Developing an epithelial signature for prognosis of papillary thyroid carcinoma.Endocr Relat Cancer202642447050PubTator, text miningPubMed
Stanniocalcin 1 at the nexus of calcium homeostasis, IGF signaling, and cancer immunity.Endocr Rev202642446003PubTator, text miningPubMed
Identification of genes differentially expressed in granulosa cells from women with high vs. low ovarian responsiveness.Front Reprod Health202642358728PubTator, text miningPubMed
Establishment of rapid identification methods of menstrual blood based on SHERLOCK technology.Int J Legal Med202642322398PubTator, text miningPubMed

1 to 10 of 1,853

See all 1,853 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6781

GET https://conductscience.org/api/genes/v1/6781/patents?page=2