ConductScience.org, home

Gene · 6788

STK3: serine/threonine kinase 3

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. STK3: serine/threonine kinase 3. Genes, record 6788. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6788

On this page

Gene

Symbol
STK3
HGNC
Name
serine/threonine kinase 3
HGNC
NCBI Gene ID
6788
NCBI Gene
HGNC ID
HGNC:11406
HGNC
Ensembl
ENSG00000104375
NCBI Gene
Aliases
KRS1, MST2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q13188Serine/threonine-protein kinase 349111Ensembl, GeneID, HGNC

Source UniProt

Patents28

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1912381Q13188Espacenet
EP 4641201 A22025-10-2913524Q13188Espacenet
JP 2025517969 A2025-06-1213524Q13188Espacenet
JP 2025517970 A2025-06-1212381Q13188Espacenet
JP 2025032204 A2025-03-1136709Q13188Espacenet
EP 4461818 A22024-11-1336709Q13188Espacenet
JP 2023058610 A2023-04-2536709Q13188Espacenet
US 11564998 B22023-01-317379Q13188Espacenet
US 11446398 B22022-09-2077871Q13188Espacenet
JP 2022524081 A2022-04-27180842Q13188Espacenet

1 to 10 of 28

See all 28 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,155

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSTK3 papersNewest fiscal year
P30CA016672Cancer Center Support Grant172025
P30CA006927Comprehensive Cancer Center Program at Fox Chase102025
T32DK007028Training Program in Endocrinology72025
R01EY015708Control of Cell Number in Developing Retina62025
P30CA030199Cancer Center Support Grant (CCSG)52025
P30DK040561Boston Area Nutrition Obesity Research Center (NORC)52025
R35GM118063Cell signaling in development and regeneration52025
T32CA009110Training in Areas Fundamental to Cancer Research52025
P30CA008748Cancer Center Support Grant42025
P30CA076292Moffitt Cancer Center Support Grant42025

1 to 10 of 1,155Source NIH's project files

See all 1,155 nih grants

Papers1,840

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Yorkie/YAP Interactors: Fine-Tuning the Hippo Pathway Output.Cold Spring Harb Perspect Biol202642575696PubTator, text miningPubMed
Alteration in the Yap Signaling Pathway in Cataractous Human Lens Epithelium.Curr Eye Res202642494054PubTator, text miningPubMed
TEAD1 condensates are transcriptionally inactive storage sites on the pericentromeric heterochromatin in cancer cells.Nat Cell Biol202642277434PubTator, text miningPubMed
Kinase condensates enrich ATP and trigger autophosphorylation.Cell Rep202642225071PubTator, text miningPubMed
The Regulation and Function of Hippo/YAP Pathway in Cancer.FASEB J202641924992PubTator, text miningPubMed
Interaction of mtROS-Immune-Inflammatory Vicious Cycle Activation in Sepsis-Induced Cardiomyopathy.Clin Exp Pharmacol Physiol202641905969PubTator, text miningPubMed
Strip1 Is a Novel Negative Regulator of Cardiomyocyte Hypertrophy.Cells202641892331PubTator, text miningPubMed
Reactive oxygen species (ROS) in cancer: from mechanism to therapeutic implications.Signal Transduct Target Ther202641881983PubTator, text miningPubMed
TRIM21-Mediated ubiquitination of FBL suppresses PI3K/AKT signaling and tumor progression in clear cell renal cell carcinoma.Cell Mol Life Sci202641863623PubTator, text miningPubMed
The EHMT2-MBLAC2 axis suppresses ribosomal DNA transcription in response to nucleolar DNA damage.Cell Death Dis202641851073PubTator, text miningPubMed

1 to 10 of 1,840

See all 1,840 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6788

GET https://conductscience.org/api/genes/v1/6788/patents?page=2