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STK11: serine/threonine kinase 11

1 protein, 69 patents, 0 drugs, 0 trials, 6,046 NIH grants and 14,866 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSTK11HGNC
Nameserine/threonine kinase 11HGNC
NCBI Gene ID6794NCBI Gene
HGNC IDHGNC:11389HGNC
EnsemblENSG00000118046NCBI Gene
AliasesLKB1, PJS, hLKB1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q15831Serine/threonine-protein kinase STK114334Ensembl, GeneID, HGNCUniProt

Patents 69

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4641201 A22025-10-295209Q15831Espacenet
WO 2025184170 A12025-09-0433Q15831Espacenet
JP 2025517969 A2025-06-125209Q15831Espacenet
US 12195490 B22025-01-143Q15831Espacenet
US 12144791 B22024-11-193Q15831Espacenet
US 12130292 B22024-10-2928Q15831Espacenet
JP 2024123008 A2024-09-108343Q15831Espacenet
US 11944615 B22024-04-022Q15831Espacenet
JP 2024513966 A2024-03-275Q15831Espacenet
KR 1020230170695 A2023-12-195Q15831Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 6046

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant2552,025NIH's project files
P30CA008748Cancer Center Support Grant1832,025NIH's project files
P01CA120964Molecular Pathogenesis of the Hamartoma Syndromes592,025NIH's project files
P30CA006973Regional Oncology Research Center472,025NIH's project files
P30CA138292Winship Cancer Institute Cancer Center Support Grant292,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase282,025NIH's project files
P30CA033572Cancer Center Support Grant262,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award262,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant252,025NIH's project files
P30CA142543UT Southwestern Medical Center Simmons Comprehensive Cancer Center252,025NIH's project files

Papers 14866

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42817222PubTator, text miningPubMed
42808379PubTator, text miningPubMed
42794785PubTator, text miningPubMed
42762608PubTator, text miningPubMed
42760391PubTator, text miningPubMed
42755510PubTator, text miningPubMed
42747979PubTator, text miningPubMed
42744683PubTator, text miningPubMed
42738389PubTator, text miningPubMed
42738366PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license