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Gene · 6804

STX1A: syntaxin 1A

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. STX1A: syntaxin 1A. Genes, record 6804. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6804

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Gene

Symbol
STX1A
HGNC
Name
syntaxin 1A
HGNC
NCBI Gene ID
6804
NCBI Gene
HGNC ID
HGNC:11433
HGNC
Ensembl
ENSG00000106089
NCBI Gene
Aliases
HPC-1, P35-1, STX1, SYN1A, p35-1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q16623Syntaxin-1A2880Ensembl, GeneID, HGNC

Source UniProt

Patents82

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1466238Q16623Espacenet
JP 2025533447 A2025-10-0737Q16623Espacenet
WO 2025196445 A12025-09-2530Q16623Espacenet
JP 2025529142 A2025-09-044506Q16623Espacenet
US 12371689 B22025-07-294506Q16623Espacenet
KR 1020250069908 A2025-05-2037Q16623Espacenet
JP 2025038035 A2025-03-184368Q16623Espacenet
US 12134655 B22024-11-054368Q16623Espacenet
US 11788069 B22023-10-1727Q16623Espacenet
US 11634458 B22023-04-252Q16623Espacenet

1 to 10 of 82

See all 82 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,640

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSTX1A papersNewest fiscal year
R01MH061876Synaptotagmin C2B Domain as a Ca2+ Sensing Module102025
ZIANS002946Axonal transport of endolysosomal organelles and presynaptic cargos for the maintenance of axon cellular homeostasis and presynaptic function72025
R01MH063105Molecular mechanisms of synaptic neurotransmitter release62025
P30CA016672Cancer Center Support Grant52025
P30DK040561Boston Area Nutrition Obesity Research Center (NORC)52025
R28AA012725Brain Tissue Resource Center for Alcohol Research52025
P30DK052574Host-environment interactions in the pathophysiology of digestive disease42025
P30CA008748Cancer Center Support Grant32025
P30CA118100University of New Mexico Cancer Center Support Grant32025
P30DK020593Vanderbilt Diabetes Research Center32025

1 to 10 of 1,640Source NIH's project files

See all 1,640 nih grants

Papers3,176

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Functional profiling of STXBP1 missense variants using a novel dual-readout fluorometric assay.Epilepsia202642811883PubTator, text miningPubMed
The antibiotic NAB815 does not induce SOS response and toxin production in Shiga toxin-producing Escherichia coli at sub-bactericidal concentrations.Int J Med Microbiol202642731261PubTator, text miningPubMed
Syntaxin-3 Regulates Tight Junction Assembly in Human Retinal Pigment Epithelium.Cell Biochem Funct202642695327PubTator, text miningPubMed
Role of STX1A in Parkinson's disease: evidence, mechanistic hypotheses, and translational perspectives.Front Aging Neurosci202642676507PubTator, text miningPubMed
Structural Basis of Shiga Toxin Neutralization by Human Antibodies Targeting Canonical Receptor-Binding and Non-Canonical Assembly Sites.Adv Sci (Weinh)202642669652PubTator, text miningPubMed
Oligomeric Alpha-Synuclein from neural-derived extracellular vesicles as possible biomarkers of non-motor symptoms in Parkinson's disease.NPJ Parkinsons Dis202642649220PubTator, text miningPubMed
Lipid Disorder and PIP2-Regulated Clustering of Syntaxin-1 JMD-TMD Regions Govern Membrane Fusion Competence.Int J Mol Sci202642589331PubTator, text miningPubMed
Munc18 binds to and organizes membrane-bound acceptor Q-SNARE complexes in a fashion that depends on the membrane's lipid composition.bioRxiv202642523309PubTator, text miningPubMed
Prevalence, virulence profiles and antibiotic susceptibility patterns of Shiga toxin producing Escherichia coli O157:H7 among children 6-59 months in Longido, Arusha-Tanzania.PLoS One202642430368PubTator, text miningPubMed
SNAREopathy in Neurologic Disorders: From Synaptic Mechanisms to Genetic and Epigenetic Regulation.Neuroscientist202642403099PubTator, text miningPubMed

1 to 10 of 3,176

See all 3,176 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6804

GET https://conductscience.org/api/genes/v1/6804/patents?page=2