Gene · 6804
STX1A: syntaxin 1A
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. STX1A: syntaxin 1A. Genes, record 6804. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6804
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q16623 | Syntaxin-1A | 288 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents82
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 66238 | Q16623 | Espacenet |
| JP 2025533447 A | 2025-10-07 | 37 | Q16623 | Espacenet |
| WO 2025196445 A1 | 2025-09-25 | 30 | Q16623 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 4506 | Q16623 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 4506 | Q16623 | Espacenet |
| KR 1020250069908 A | 2025-05-20 | 37 | Q16623 | Espacenet |
| JP 2025038035 A | 2025-03-18 | 4368 | Q16623 | Espacenet |
| US 12134655 B2 | 2024-11-05 | 4368 | Q16623 | Espacenet |
| US 11788069 B2 | 2023-10-17 | 27 | Q16623 | Espacenet |
| US 11634458 B2 | 2023-04-25 | 2 | Q16623 | Espacenet |
1 to 10 of 82
See all 82 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,640
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | STX1A papers | Newest fiscal year |
|---|---|---|---|
| R01MH061876 | Synaptotagmin C2B Domain as a Ca2+ Sensing Module | 10 | 2025 |
| ZIANS002946 | Axonal transport of endolysosomal organelles and presynaptic cargos for the maintenance of axon cellular homeostasis and presynaptic function | 7 | 2025 |
| R01MH063105 | Molecular mechanisms of synaptic neurotransmitter release | 6 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
| P30DK040561 | Boston Area Nutrition Obesity Research Center (NORC) | 5 | 2025 |
| R28AA012725 | Brain Tissue Resource Center for Alcohol Research | 5 | 2025 |
| P30DK052574 | Host-environment interactions in the pathophysiology of digestive disease | 4 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P30CA118100 | University of New Mexico Cancer Center Support Grant | 3 | 2025 |
| P30DK020593 | Vanderbilt Diabetes Research Center | 3 | 2025 |
1 to 10 of 1,640Source NIH's project files
See all 1,640 nih grantsPapers3,176
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Functional profiling of STXBP1 missense variants using a novel dual-readout fluorometric assay. | Epilepsia | 2026 | 42811883 | PubTator, text mining | PubMed |
| The antibiotic NAB815 does not induce SOS response and toxin production in Shiga toxin-producing Escherichia coli at sub-bactericidal concentrations. | Int J Med Microbiol | 2026 | 42731261 | PubTator, text mining | PubMed |
| Syntaxin-3 Regulates Tight Junction Assembly in Human Retinal Pigment Epithelium. | Cell Biochem Funct | 2026 | 42695327 | PubTator, text mining | PubMed |
| Role of STX1A in Parkinson's disease: evidence, mechanistic hypotheses, and translational perspectives. | Front Aging Neurosci | 2026 | 42676507 | PubTator, text mining | PubMed |
| Structural Basis of Shiga Toxin Neutralization by Human Antibodies Targeting Canonical Receptor-Binding and Non-Canonical Assembly Sites. | Adv Sci (Weinh) | 2026 | 42669652 | PubTator, text mining | PubMed |
| Oligomeric Alpha-Synuclein from neural-derived extracellular vesicles as possible biomarkers of non-motor symptoms in Parkinson's disease. | NPJ Parkinsons Dis | 2026 | 42649220 | PubTator, text mining | PubMed |
| Lipid Disorder and PIP2-Regulated Clustering of Syntaxin-1 JMD-TMD Regions Govern Membrane Fusion Competence. | Int J Mol Sci | 2026 | 42589331 | PubTator, text mining | PubMed |
| Munc18 binds to and organizes membrane-bound acceptor Q-SNARE complexes in a fashion that depends on the membrane's lipid composition. | bioRxiv | 2026 | 42523309 | PubTator, text mining | PubMed |
| Prevalence, virulence profiles and antibiotic susceptibility patterns of Shiga toxin producing Escherichia coli O157:H7 among children 6-59 months in Longido, Arusha-Tanzania. | PLoS One | 2026 | 42430368 | PubTator, text mining | PubMed |
| SNAREopathy in Neurologic Disorders: From Synaptic Mechanisms to Genetic and Epigenetic Regulation. | Neuroscientist | 2026 | 42403099 | PubTator, text mining | PubMed |
1 to 10 of 3,176
See all 3,176 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/6804
GET https://conductscience.org/api/genes/v1/6804/patents?page=2