Gene · 6812
STXBP1: syntaxin binding protein 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. STXBP1: syntaxin binding protein 1. Genes, record 6812. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6812
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P61764 | Syntaxin-binding protein 1 | 594 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents31
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 66261 | P61764 | Espacenet |
| WO 2025250031 A1 | 2025-12-04 | 2 | P61764 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 9290 | P61764 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 5579 | P61764 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 9290 | P61764 | Espacenet |
| WO 2025122543 A1 | 2025-06-12 | 6413 | P61764 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 5579 | P61764 | Espacenet |
| JP 2024543001 A | 2024-11-19 | 10 | P61764 | Espacenet |
| WO 2024229167 A1 | 2024-11-07 | 6413 | P61764 | Espacenet |
| KR 1020240099360 A | 2024-06-28 | 10 | P61764 | Espacenet |
1 to 10 of 31
See all 31 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,174
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | STXBP1 papers | Newest fiscal year |
|---|---|---|---|
| U24NS120854 | ClinGen Expert Curation Panel for the Epilepsies | 10 | 2025 |
| UL1TR001878 | Institutional Clinical and Translational Science Award | 10 | 2025 |
| R01MH101221 | Rare Mutations and Autism Spectrum Disorders | 9 | 2025 |
| R35GM131714 | Single-molecule studies of SNARE assembly and lipid transfer | 6 | 2025 |
| P40OD010440 | Caenorhabditis Genetics Center | 5 | 2025 |
| R01NS127830 | Subgroup delineation in genetic epilepsies and developmental brain disorders | 4 | 2025 |
| R01NS131512 | A computational phenotyping approach to characterize neurogenetic disorders | 4 | 2025 |
| R35GM126960 | Discovering protein networks underlying regulated exocytosis | 4 | 2025 |
| T32HG000035 | Interdisciplinary Training in Genome Sciences | 4 | 2025 |
| K12NS098482 | Child Neurologist Career Development Program | 3 | 2025 |
1 to 10 of 1,174Source NIH's project files
See all 1,174 nih grantsPapers1,814
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Functional profiling of STXBP1 missense variants using a novel dual-readout fluorometric assay. | Epilepsia | 2026 | 42811883 | PubTator, text mining | PubMed |
| Gene-specific machine learning model EpiPred identifies likely pathogenic variants in the epilepsy-related gene STXBP1. | J Clin Invest | 2026 | 42752354 | PubTator, text mining | PubMed |
| [Effectiveness and tolerability of ketogenic diet therapy in children with genetic developmental and epileptic encephalopathy onset within 2 years of age]. | Zhonghua Er Ke Za Zhi | 2026 | 42742013 | PubTator, text mining | PubMed |
| Genomic Sequencing in Neonatal Encephalopathy and Suspected Hypoxic-Ischaemic Encephalopathy: A Systematic Review. | Genes (Basel) | 2026 | 42650055 | PubTator, text mining | PubMed |
| Tumor suppressor syntaxin binding protein 1 regulates alternative splicing of DNA repair genes related to radiation sensitivity in breast cancer cells. | Oncol Lett | 2026 | 42631023 | PubTator, text mining | PubMed |
| STXBP1 Variants Associated With Epilepsy With Variable Severity. | CNS Neurosci Ther | 2026 | 42609058 | PubTator, text mining | PubMed |
| Early infantile developmental and epileptic encephalopathy: clinical spectrum, diagnosis, outcomes, and evolving treatment strategies. | Brain Dev | 2026 | 42607558 | PubTator, text mining | PubMed |
| Diagnostic delay in infants with very early-onset rare and ultra-rare genetic epilepsies. | Dev Med Child Neurol | 2026 | 42573089 | PubTator, text mining | PubMed |
| Functional differences of Munc18 isoforms reflect their affinities for the exocytosis site. | Cell Mol Life Sci | 2026 | 42570027 | PubTator, text mining | PubMed |
| Associations of Cortical and Subcortical White Matter Morphometric Abnormalities With Clinical and Genetic Findings in STXBP1 Encephalopathy. | Neurol Genet | 2026 | 42559425 | PubTator, text mining | PubMed |
1 to 10 of 1,814
See all 1,814 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/6812
GET https://conductscience.org/api/genes/v1/6812/patents?page=2