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Gene · 685

BTC: betacellulin

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. BTC: betacellulin. Genes, record 685. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/685

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Gene

Symbol
BTC
HGNC
Name
betacellulin
HGNC
NCBI Gene ID
685
NCBI Gene
HGNC ID
HGNC:1121
HGNC
Ensembl
ENSG00000174808
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P35070Probetacellulin1784Ensembl, GeneID, HGNC

Source UniProt

Patents68

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026067859 A2026-04-21156P35070Espacenet
EP 4650780 A22025-11-1911311P35070Espacenet
EP 4640849 A22025-10-291760P35070Espacenet
EP 4641201 A22025-10-2911783P35070Espacenet
JP 2025138725 A2025-09-252685P35070Espacenet
JP 2025529142 A2025-09-04607P35070Espacenet
EP 4606428 A22025-08-2715P35070Espacenet
US 12371689 B22025-07-29607P35070Espacenet
EP 4587837 A12025-07-2355P35070Espacenet
JP 2025519096 A2025-06-241760P35070Espacenet

1 to 10 of 68

See all 68 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,104

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleBTC papersNewest fiscal year
P30CA068485Cancer Center Support Grant132025
P30CA016672Cancer Center Support Grant102025
P30DK058404Molecular and Cellular Basis for Digestive Diseases52025
P30EY008126Core Grant in Vision Research52025
P30CA006927Comprehensive Cancer Center Program at Fox Chase42025
P30CA008748Cancer Center Support Grant42025
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202842025
P30DK020593Vanderbilt Diabetes Research Center42025
T32CA009582Biochemical and Chemical Training for Cancer Research42025
P30CA023168Cancer Center Support Grant32025

1 to 10 of 1,104Source NIH's project files

See all 1,104 nih grants

Papers1,437

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Exploring and validating hub genes associated with atopic dermatitis through weighted gene co-expression network analysis and machine learning.Medicine (Baltimore)202642629711PubTator, text miningPubMed
Detecting Unusual Trading Patterns on Cryptocurrency Exchanges by Means of Complexity Measures.Entropy (Basel)202642511413PubTator, text miningPubMed
A review of epidermal growth factor receptor ligands in glucose homeostasis.Front Endocrinol (Lausanne)202642290844PubTator, text miningPubMed
Growth factor betacellulin can stimulate human granulosa cell functions and promote gonadotropin actions.Mol Biol Rep202642240693PubTator, text miningPubMed
HNRNPDL facilitates the advancement of non-small cell lung carcinoma via modulating the alternative splicing of the BTC gene.Immunobiology202641861445PubTator, text miningPubMed
Phase Ib multicenter study of anti-TIM-3 (S095018/Sym023) in combination with anti-PD-1 (Sym021) in patients with advanced/metastatic recurrent biliary tract cancer.J Immunother Cancer202641825935PubTator, text miningPubMed
Maternal docosahexaenoic acid and eicosapentaenoic acid supplementation: effects and mechanisms on lipid metabolism in the offspring.Front Nutr202641798834PubTator, text miningPubMed
Dynamic dual regulation of amphiregulin in liver pathophysiology: balancing regeneration and disease progression via the EGFR axis.Front Med (Lausanne)202641788718PubTator, text miningPubMed
The ADAM Family of Proteases: Structure, Substrates, and Roles in Liver Diseases.Int J Mol Sci202641751763PubTator, text miningPubMed
In vitro cytotoxicity of medicinal plants used in prostate cancer management in Africa: a systematic review.Trop Med Health202641709315PubTator, text miningPubMed

1 to 10 of 1,437

See all 1,437 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/685

GET https://conductscience.org/api/genes/v1/685/patents?page=2