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Gene · 6853

SYN1: synapsin I

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SYN1: synapsin I. Genes, record 6853. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6853

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Gene

Symbol
SYN1
HGNC
Name
synapsin I
HGNC
NCBI Gene ID
6853
NCBI Gene
HGNC ID
HGNC:11494
HGNC
Ensembl
ENSG00000008056
NCBI Gene
Aliases
EPILX, EPILX1, MRX50, SYN1a, SYN1b, SYNI
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P17600Synapsin-17050Ensembl, GeneID, HGNC

Source UniProt

Patents20

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026079407 A2026-04-16107P17600Espacenet
JP 2026004568 A2026-01-1466012P17600Espacenet
EP 4516316 A12025-03-05107P17600Espacenet
WO 2023210585 A2023-11-02107P17600Espacenet
JP 2023086836 A2023-06-2290P17600Espacenet
JP 2023505833 A2023-02-1390P17600Espacenet
US 11446398 B22022-09-2085503P17600Espacenet
JP 2022524081 A2022-04-27188474P17600Espacenet
JP 2021535746 A2021-12-2390P17600Espacenet
US 11078247 B22021-08-0311222P17600Espacenet

1 to 10 of 20

See all 20 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants3,319

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSYN1 papersNewest fiscal year
ZIAAG000936Alzheimers Disease Project: Neuroimmune responses and therapeutics of alpha-synucleinopathies of the aging population92025
P51OD011132Emory National Primate Research Center82025
P30CA008748Cancer Center Support Grant72025
P30DA018343Yale/NIDA Neuroproteomics Center72025
P30CA014195Cancer Center Support Grant (CCSG)62025
R01MH100175Proteogenetics of Autism Spectrum Disorders62025
P01AG019724Frontotemporal Dementia: Genes, Images, and Emotions42025
P01DA047233Transcriptional Mechanisms of Drug Addiction42025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant42025
P30EY003176UC Berkeley Vision Science CORE42025

1 to 10 of 3,319Source NIH's project files

See all 3,319 nih grants

Papers3,694

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Acute effects of whole-body vibration training with additional loading on lower limb muscle synergies during running.Acta Bioeng Biomech202642809351PubTator, text miningPubMed
Lumbrokinase ameliorates chronic social defeat stress-induced behavioral impairments through modulation of miR-340-5p and SUMO2 signaling.Neuropharmacology202642716376PubTator, text miningPubMed
Neurofunctional gradients and molecular signatures underlying problematic smartphone use: A connectomic, psychological, and transcriptomic study.Prog Neuropsychopharmacol Biol Psychiatry202642697356PubTator, text miningPubMed
In Silico and In Vitro Evaluation of Calm Supplement Constituents on Antidepressant-Related Molecular Targets and Neuroplasticity-Associated Gene Expression.Biomedicines202642652132PubTator, text miningPubMed
RNA Promotes Synapsin Condensates That Organize Synaptic Vesicles in Live Neurons and Enable Localized Translation in Reconstituted System.Adv Sci (Weinh)202642627687PubTator, text miningPubMed
Epilepsy-associated SCN2A-L1342P mutation drives network hyperexcitability and widespread transcriptomic changes in human cortical organoids.Epilepsia202642530523PubTator, text miningPubMed
Restoring Parkin Function: An AAV Gene Therapy Approach for Early-Onset Parkinson's Disease.bioRxiv202642523270PubTator, text miningPubMed
Developmentally sensitive neuropharmacological effects of dexamethasone in neonatal bronchopulmonary dysplasia-associated brain injury via microglial Acod1-itaconate/IL-1β signaling.Front Pharmacol202642488574PubTator, text miningPubMed
Renal and endothelial biomarkers in Chagas disease in the Brazilian Amazon region: Early indicators of kidney injury and disease progression.PLoS One202642467670PubTator, text miningPubMed
Neuron-specific WWOX gene therapy produces dose-dependent, durable rescue in a model of WWOX-related epileptic encephalopathy.Mol Ther Adv202642422765PubTator, text miningPubMed

1 to 10 of 3,694

See all 3,694 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6853

GET https://conductscience.org/api/genes/v1/6853/patents