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Gene · 6866

TAC3: tachykinin precursor 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TAC3: tachykinin precursor 3. Genes, record 6866. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6866

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Gene

Symbol
TAC3
HGNC
Name
tachykinin precursor 3
HGNC
NCBI Gene ID
6866
NCBI Gene
HGNC ID
HGNC:11521
HGNC
Ensembl
ENSG00000166863
NCBI Gene
Aliases
HH10, LncZBTB39, LncZBTB39-1:2, NK3, NKB, NKNB, PRO1155, ZNEUROK1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9UHF0Tachykinin-31212Ensembl, GeneID, HGNC

Source UniProt

Patents87

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1466337Q9UHF0Espacenet
JP 2026004568 A2026-01-1466338Q9UHF0Espacenet
JP 2026004568 A2026-01-1466340Q9UHF0Espacenet
EP 4650780 A22025-11-193984Q9UHF0Espacenet
JP 2025147176 A2025-10-0612999Q9UHF0Espacenet
JP 2025147176 A2025-10-0613000Q9UHF0Espacenet
JP 2025147176 A2025-10-0613001Q9UHF0Espacenet
JP 2025147176 A2025-10-0613002Q9UHF0Espacenet
JP 2025529142 A2025-09-047845Q9UHF0Espacenet
US 12371689 B22025-07-297845Q9UHF0Espacenet

1 to 10 of 87

See all 87 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants871

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTAC3 papersNewest fiscal year
P51OD011092Support for National Primate Research Center192025
R01HD082314Deciphering the functional role of MKRN3 in puberty and reproduction162025
P51OD011106Wisconsin National Primate Research Center Support92025
P30DA018310Neurometabolomics and Neuroproteomics Center on Cell-Cell Signaling42025
R37HD019938Reproductive physiology of gonadotropin synthesis42025
T32DK007529Training Grant in Academic Endocrinology42025
T32HD007203Training in Reproductive Sciences42025
R37HD043341Towards Curative Therapies for Hypogonadotropic Diseases32025
P20GM103434West Virginia IDeA Network of Biomedical Research Excellence (WV-INBRE)22025
P30DA048736University of Washington Center of Excellence in Opioid Addiction Research22025

1 to 10 of 871Source NIH's project files

See all 871 nih grants

Papers1,815

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Kisspeptin-10/basal LH ratio improves differentiation of central precocious puberty and premature thelarche.Clin Chim Acta202742364891PubTator, text miningPubMed
Obesity, Oxidative Stress, and Inflammation in Precocious Puberty: Do All Roads Lead to the Hypothalamus?Int J Mol Sci202642794587PubTator, text miningPubMed
Precocious puberty in boys: current insights into etiology, genetic advances, and environmental factors.Front Endocrinol (Lausanne)202642534783PubTator, text miningPubMed
Identification of a Novel Splice-Site variant in TACR3 (c.888 + 1G > A) Associated with Asthenozoospermia and Hypogonadotropic Hypogonadism in an Iranian Family.Reprod Sci202642521916PubTator, text miningPubMed
A brain-first framework for perimenopause management: the case for non-invasive neuromodulation.Front Glob Womens Health202642519421PubTator, text miningPubMed
Progressive hypothalamic neuroinflammation in ovariectomized mice parallels aging-related transcriptomic changes in the female human hypothalamus.JCI Insight202642490144PubTator, text miningPubMed
Hot flashes: a review.Front Med (Lausanne)202642428273PubTator, text miningPubMed
Neuroendocrine mechanisms of stress-induced KNDy-GnRH pulse generator suppression: Linking HPA-axis activation to female reproductive dysfunction.Front Neuroendocrinol202642401315PubTator, text miningPubMed
Examining a central mechanism whereby undernutrition inhibits GnRH secretion via KNDy neurons.J Reprod Dev202642309752PubTator, text miningPubMed
Missense mutations in MKRN3 and central precocious puberty: a mutational approach to understanding protein function.Curr Opin Pediatr202642290210PubTator, text miningPubMed

1 to 10 of 1,815

See all 1,815 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

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