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TACR1: tachykinin receptor 1

1 protein, 43 patents, 20 drugs, 109 trials, 2,376 NIH grants and 5,134 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolTACR1HGNC
Nametachykinin receptor 1HGNC
NCBI Gene ID6869NCBI Gene
HGNC IDHGNC:11526HGNC
EnsemblENSG00000115353NCBI Gene
AliasesNK1R, NKIR, SPR, TAC1RNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P25103Substance-P receptor40715Ensembl, GeneID, HGNCUniProt

Patents 43

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1466341P25103Espacenet
EP 4641201 A22025-10-293777P25103Espacenet
JP 2025529142 A2025-09-044570P25103Espacenet
US 12371689 B22025-07-294570P25103Espacenet
JP 2025517969 A2025-06-123777P25103Espacenet
US 11446398 B22022-09-2086503P25103Espacenet
JP 2022534990 A2022-08-041P25103Espacenet
US 11400116 B22022-08-02939P25103Espacenet
JP 2022524081 A2022-04-27189474P25103Espacenet
US 11124834 B22021-09-21237P25103Espacenet

Drugs 20

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
APREPITANTCHEMBL1471Neurokinin 1 receptor antagonistANTAGONISTChEMBL
BURAPITANTCHEMBL3544947Neurokinin 1 receptor antagonistANTAGONISTChEMBL
CASOPITANTCHEMBL1672054Neurokinin 1 receptor antagonistANTAGONISTChEMBL
DNK333CHEMBL105060Neurokinin 1 receptor antagonistANTAGONISTChEMBL
ELINZANETANTCHEMBL4802157Neurokinin 1 receptor antagonistANTAGONISTChEMBL
EZLOPITANTCHEMBL515966Neurokinin 1 receptor antagonistANTAGONISTChEMBL
FIGOPITANTCHEMBL2104927Neurokinin 1 receptor antagonistANTAGONISTChEMBL
FOSAPREPITANTCHEMBL1199324Neurokinin 1 receptor antagonistANTAGONISTChEMBL
FOSAPREPITANT DIMEGLUMINECHEMBL1201782Neurokinin 1 receptor antagonistANTAGONISTChEMBL
FOSNETUPITANTCHEMBL3989917Neurokinin 1 receptor antagonistANTAGONISTChEMBL

Trials 109

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07446439TRADIPITANTPHASE3ClinicalTrials.gov
NCT07077395ELINZANETANTPHASE2ClinicalTrials.gov
NCT06931119APREPITANTPHASE1ClinicalTrials.gov
NCT06836557TRADIPITANTPHASE3ClinicalTrials.gov
NCT06462287APREPITANTPHASE2ClinicalTrials.gov
NCT06382012FOSAPREPITANTPHASE2/PHASE3ClinicalTrials.gov
NCT06382012APREPITANTPHASE2/PHASE3ClinicalTrials.gov
NCT06317064APREPITANTPHASE3ClinicalTrials.gov
NCT06138613TRADIPITANTPHASE3ClinicalTrials.gov
NCT06112756ELINZANETANTPHASE22025-11-10ClinicalTrials.gov

NIH grants 2376

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant92,025NIH's project files
T32GM007569Clinical Pharmacology Training Program72,025NIH's project files
P30MH097488Penn Mental Health AIDS Research Center62,025NIH's project files
R01NS102722Endosomal Platforms for Signaling Pain62,025NIH's project files
P30CA016672Cancer Center Support Grant52,025NIH's project files
P30CA047904Cancer Center Support Grant52,025NIH's project files
P51OD011104Tulane National Primate Research Center52,025NIH's project files
R01DA008863Regulation Of Opioid Receptor Signaling by Endogenous Peptides52,025NIH's project files
R01EY020889Immunopathogenic Mechanisms of Dry Eye Disease52,025NIH's project files
P30AI045008Penn Center for AIDS Research42,025NIH's project files

Papers 5134

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42795776PubTator, text miningPubMed
42793284PubTator, text miningPubMed
42765558PubTator, text miningPubMed
42761320PubTator, text miningPubMed
42756130PubTator, text miningPubMed
42729896PubTator, text miningPubMed
42725596PubTator, text miningPubMed
42724479PubTator, text miningPubMed
42701103PubTator, text miningPubMed
42692233PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license