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Gene · 687

KLF9: KLF transcription factor 9

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. KLF9: KLF transcription factor 9. Genes, record 687. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/687

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Gene

Symbol
KLF9
HGNC
Name
KLF transcription factor 9
HGNC
NCBI Gene ID
687
NCBI Gene
HGNC ID
HGNC:1123
HGNC
Ensembl
ENSG00000119138
NCBI Gene
Aliases
BTEB, BTEB1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q13886Krueppel-like factor 92440Ensembl, GeneID, HGNC

Source UniProt

Patents60

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-199884Q13886Espacenet
EP 4647503 A12025-11-1272Q13886Espacenet
JP 2025147176 A2025-10-0615223Q13886Espacenet
KR 1020250133892 A2025-09-0972Q13886Espacenet
JP 2025517970 A2025-06-129884Q13886Espacenet
JP 2025028160 A2025-02-2815223Q13886Espacenet
KR 1020250010750 A2025-01-2115223Q13886Espacenet
JP 2024109657 A2024-08-1415062Q13886Espacenet
WO 2024147344 A2024-07-1172Q13886Espacenet
JP 2024519218 A2024-05-09124Q13886Espacenet

1 to 10 of 60

See all 60 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,027

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleKLF9 papersNewest fiscal year
P30CA016056Roswell Park Cancer Center Support Grant52025
P30CA016672Cancer Center Support Grant42025
P30DK084567Mayo Center for Cell Signaling in Gastroenterology42025
P30EY014801Miami Center for Vision Research42025
ZIAES103311Environmental Signaling in Reproduction and Pregnancy42025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant32025
P30EY026877Stanford Vision Research Core32025
R01DK052230Regulation of Intestinal Epithelial Cell Proliferation32025
R01HL109557Mechanisms and Consequences of Gene Induction by Glucocorticoids in Airway Smooth Muscle32025
T32HD079342Career Training in Reproductive Biology32025

1 to 10 of 1,027Source NIH's project files

See all 1,027 nih grants

Papers1,282

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Survival-Associated Molecular and Epigenetic Alterations in Endocervical Adenocarcinoma: An Exploratory TCGA Multi-Omics Cohort Study.Curr Issues Mol Biol202642793237PubTator, text miningPubMed
Paedomorphic Patterns of Gene Expression in the Eyes of Brook Salamanders.Integr Comp Biol202642747168PubTator, text miningPubMed
Mitocurcumin disrupts glutathione balance by modulating Klf9/GSR axis to overcome platinum resistance in non-small cell lung cancer and restores immune surveillance in cold tumor.Free Radic Biol Med202642607819PubTator, text miningPubMed
A Glucocorticoid-KLF9-CHCHD10 Axis Governs Mitochondrial Resilience in Radiation-Induced Lung Injury.Antioxid Redox Signal202642486791PubTator, text miningPubMed
Mesenchymal stem cells receive adaptive islet-derived miR-151-containing sEVs to promote β cell compensation in obesity.Sci Adv202642467765PubTator, text miningPubMed
Nrf2 promotes NLRP3 inflammasome assembly and activation by Klf9-TXNIP axis.Cell Death Discov202642362500PubTator, text miningPubMed
Comparative Evaluation of hiPSC-Derived Brain Organoids as Platforms for Assessing Thyroid Hormone System Disrupting Chemicals.Cells202642274556PubTator, text miningPubMed
Acellular normothermic spleen perfusion resolves transcriptional and non-transcriptional mechanisms of steroid immunosuppression.bioRxiv202642239436PubTator, text miningPubMed
Endothelial Klf9 fine-tunes Akt signaling to act as a transcriptional brake restraining retinal angiogenesis.Int J Biol Sci202642212336PubTator, text miningPubMed
Loss of Peroxiredoxin 6 Drives Age-Related Klf9/NF-κB/Nlrp3 Inflammasome Activation and Pyroptosis: Therapeutic Rescue by Prdx6.Antioxidants (Basel)202642193155PubTator, text miningPubMed

1 to 10 of 1,282

See all 1,282 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/687

GET https://conductscience.org/api/genes/v1/687/patents?page=2