Gene · 688
KLF5: KLF transcription factor 5
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. KLF5: KLF transcription factor 5. Genes, record 688. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/688
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q13887 | Krueppel-like factor 5 | 457 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents64
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2025147176 A | 2025-10-06 | 15219 | Q13887 | Espacenet |
| EP 4553154 A1 | 2025-05-14 | 7 | Q13887 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15219 | Q13887 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15219 | Q13887 | Espacenet |
| JP 2024160262 A | 2024-11-13 | 145 | Q13887 | Espacenet |
| KR 1020240158384 A | 2024-11-04 | 145 | Q13887 | Espacenet |
| JP 2024534404 A | 2024-09-20 | 89 | Q13887 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 15058 | Q13887 | Espacenet |
| WO 2024010085 A | 2024-01-11 | 7 | Q13887 | Espacenet |
| JP 2023114300 A | 2023-08-17 | 5 | Q13887 | Espacenet |
1 to 10 of 64
See all 64 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,225
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | KLF5 papers | Newest fiscal year |
|---|---|---|---|
| R01DK052230 | Regulation of Intestinal Epithelial Cell Proliferation | 32 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 22 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 15 | 2025 |
| P30DK050306 | Center for Molecular Studies in Digestive and Liver Diseases | 11 | 2025 |
| P30CA016520 | Abramson Cancer Center Support Grant | 8 | 2025 |
| P30CA138292 | Winship Cancer Institute Cancer Center Support Grant | 8 | 2025 |
| P30CA015083 | Mayo Clinic Comprehensive Cancer Center Support Grant | 7 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 7 | 2025 |
| P30CA014089 | University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG) | 5 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 5 | 2025 |
1 to 10 of 2,225Source NIH's project files
See all 2,225 nih grantsPapers3,365
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Molecular Mechanisms of Indoor Environmental Pollution tt-DDE-Induced Blood Pressure Elevation and the Protective Role of Human-Specific Gene CHRFAM7A. | Environ Health (Wash) | 2026 | 42775181 | PubTator, text mining | PubMed |
| KLF transcription factors in metabolic kidney disease: from podocyte protection to tubulointerstitial fibrosis. | Int Urol Nephrol | 2026 | 42753072 | PubTator, text mining | PubMed |
| KLF5-driven G6PD protects lung squamous cell carcinoma from ferroptosis by sustaining mitochondrial homeostasis and SLC7A11-dependent cystine uptake. | Int Immunopharmacol | 2026 | 42748785 | PubTator, text mining | PubMed |
| Erratum: Krüppel-like factor 5 promotes the progression of oral squamous cell carcinoma via the baculoviral IAP repeat containing 5 gene. | Ann Transl Med | 2026 | 42719264 | PubTator, text mining | PubMed |
| A recurrently perturbed 12-gene program marks drug-tolerant persister states across cancer types. | Front Bioinform | 2026 | 42682804 | PubTator, text mining | PubMed |
| PROFET predicts continuous gene expression dynamics from scRNA-seq data to elucidate heterogeneity of cancer treatment responses. | Cell Syst | 2026 | 42664975 | PubTator, text mining | PubMed |
| KLF5 Downregulation Links Impaired BNIP3-Mediated Mitophagy to Inflammatory Valve Remodeling in Calcific Aortic Valve Disease. | Adv Sci (Weinh) | 2026 | 42658612 | PubTator, text mining | PubMed |
| Probucol inhibits palmitic acid-mediated renal calcium oxalate stone formation by targeting KLF5-PPARγ axis-mediated lipotoxicity. | J Pharm Anal | 2026 | 42631108 | PubTator, text mining | PubMed |
| Regulatory roles and translational potential of the Kruppel-like factor family in liver disease. | ILIVER | 2026 | 42598083 | PubTator, text mining | PubMed |
| Molecular Mechanism of TRIM16 Regulating Osteogenic Differentiation of Periodontal Ligament Stem Cells Under Inflammatory Microenvironment. | Cell Biol Int | 2026 | 42559952 | PubTator, text mining | PubMed |
1 to 10 of 3,365
See all 3,365 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/688
GET https://conductscience.org/api/genes/v1/688/patents?page=2