ConductScience.org, home

Library / Genes

MAP3K7: mitogen-activated protein kinase kinase kinase 7

1 protein, 29 patents, 0 drugs, 0 trials, 4,695 NIH grants and 8,752 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolMAP3K7HGNC
Namemitogen-activated protein kinase kinase kinase 7HGNC
NCBI Gene ID6885NCBI Gene
HGNC IDHGNC:6859HGNC
EnsemblENSG00000135341NCBI Gene
AliasesCSCF, FMD2, MEKK7, TAK1, TGF1aNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
O43318Mitogen-activated protein kinase kinase kinase 760625Ensembl, GeneID, HGNCUniProt

Patents 29

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1453993O43318Espacenet
JP 2025524002 A2025-07-2521O43318Espacenet
KR 1020250039465 A2025-03-2021O43318Espacenet
JP 2024023699 A2024-02-2121O43318Espacenet
JP 2024505890 A2024-02-0821O43318Espacenet
JP 2023509886 A2023-03-1021O43318Espacenet
US 11446398 B22022-09-2052583O43318Espacenet
KR 1020220123023 A2022-09-0521O43318Espacenet
JP 2022524081 A2022-04-27155554O43318Espacenet
WO 2021134004 A12021-07-0121O43318Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4695

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant702,025NIH's project files
P30CA008748Cancer Center Support Grant212,025NIH's project files
R01AI124346Innate immune signaling and stress response132,025NIH's project files
R01CA097098Targeting the MUC1-C Oncoprotein in Triple-Negative Breast Cancer132,025NIH's project files
R37AI101935Inflammatory Caspases in Innate Immunity and Inflammation132,025NIH's project files
P01CA125066Discovery of Anticancer Agents of Diverse Natural Origin102,025NIH's project files
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)102,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant92,025NIH's project files
R01DK085252Extracellular Matrix Regulates Hepatic Stellate Cell Activation and Fibrosis92,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant82,025NIH's project files

Papers 8752

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42811170PubTator, text miningPubMed
42807951PubTator, text miningPubMed
42805968PubTator, text miningPubMed
42801250PubTator, text miningPubMed
42779086PubTator, text miningPubMed
42753352PubTator, text miningPubMed
42737428PubTator, text miningPubMed
42718885PubTator, text miningPubMed
42696479PubTator, text miningPubMed
42660298PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license