Gene · 6886
TAL1: TAL bHLH transcription factor 1, erythroid differentiation factor
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. TAL1: TAL bHLH transcription factor 1, erythroid differentiation factor. Genes, record 6886. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6886
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P17542 | T-cell acute lymphocytic leukemia protein 1 | 331 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents58
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2025147176 A | 2025-10-06 | 15705 | P17542 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 16608 | P17542 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15705 | P17542 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 16608 | P17542 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15705 | P17542 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 16608 | P17542 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 8610 | P17542 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 8612 | P17542 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 15544 | P17542 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 16447 | P17542 | Espacenet |
1 to 10 of 58
See all 58 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,325
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | TAL1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA021765 | Cancer Center Support Grant (CCSG) | 41 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 22 | 2025 |
| R01CA096899 | Mechanism(s) of TAL1- and NOTCH1-mediated Leukemogenesis | 15 | 2025 |
| R01DK103794 | Systematic Genetic Dissection of Human Erythropoiesis | 13 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 12 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 12 | 2025 |
| R01DK050107 | Transcriptional Control of Hemoglobin Synthesis and Erythrocyte Development | 12 | 2025 |
| R01DK068634 | Hematopoietic Regulation via GATA Switches | 12 | 2025 |
| R01DK054937 | Transcriptional Networks Controlling Erythroid Differentiation | 10 | 2025 |
| R35CA197695 | Translating genomic discoveries to improved outcomes for high risk acute leukemia | 10 | 2025 |
1 to 10 of 2,325Source NIH's project files
See all 2,325 nih grantsPapers3,225
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| KSR2 is a novel oncogene in TAL1 subtype of T-cell acute lymphoblastic leukemia with potential clinical and prognostic implications. | Haematologica | 2026 | 42610420 | PubTator, text mining | PubMed |
| TAL1 is indispensable in ETV2-primed human endothelial cell fate determination. | Sci Adv | 2026 | 42585327 | PubTator, text mining | PubMed |
| Dynamic expression of CD9 protein in T-cell acute lymphoblastic leukemia. | Cancer Gene Ther | 2026 | 42576053 | PubTator, text mining | PubMed |
| Bioinformatics identification of candidate biomarkers associated with T cell proliferation in atherosclerosis via WGCNA and machine learning. | J Cardiothorac Surg | 2026 | 42464325 | PubTator, text mining | PubMed |
| Enhanced γ-globin reactivation and sickle cell correction through a repressor-to-activator motif switch in the HBG1/2 promoters. | Mol Ther Nucleic Acids | 2026 | 42405279 | PubTator, text mining | PubMed |
| Association between tumor genomic mutations and the risk of PD-1 inhibitor-induced hypophysitis: a retrospective cohort study. | Front Endocrinol (Lausanne) | 2026 | 42339089 | PubTator, text mining | PubMed |
| Single-cell mapping of regulatory DNA-protein interactions. | Cell | 2026 | 42242226 | PubTator, text mining | PubMed |
| An integrated multi-omics analysis reveals a core epigenetically-activated transcriptional network driving oncogenic signaling in acute myeloid leukemia. | Discov Oncol | 2026 | 42217088 | PubTator, text mining | PubMed |
| Reactivation of a TAL1 progenitor cell enhancer region by non-coding somatic variants in T-lineage acute lymphoblastic leukemia. | bioRxiv | 2026 | 42146694 | PubTator, text mining | PubMed |
| Spider peptides from Brachypelma smithi with slightly different amino acids at their C-terminal loops exert different insecticidal activities. | Amino Acids | 2026 | 41957118 | PubTator, text mining | PubMed |
1 to 10 of 3,225
See all 3,225 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/6886
GET https://conductscience.org/api/genes/v1/6886/patents?page=2