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Gene · 6891

TAP2: transporter 2, ATP binding cassette subfamily B member

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TAP2: transporter 2, ATP binding cassette subfamily B member. Genes, record 6891. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6891

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Gene

Symbol
TAP2
HGNC
Name
transporter 2, ATP binding cassette subfamily B member
HGNC
NCBI Gene ID
6891
NCBI Gene
HGNC ID
HGNC:44
HGNC
Ensembl
ENSG00000204267
NCBI Gene
Aliases
ABC18, ABCB3, APT2, D6S217E, MHC1D2, PSF-2, PSF2, RING11
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q03519Antigen peptide transporter 268621Ensembl, GeneID, HGNC

Source UniProt

Patents55

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4774294 A12026-07-1521Q03519Espacenet
JP 2026004568 A2026-01-1467879Q03519Espacenet
JP 2026004568 A2026-01-1467881Q03519Espacenet
JP 2026004568 A2026-01-1467883Q03519Espacenet
JP 2026004568 A2026-01-1467889Q03519Espacenet
EP 4640849 A22025-10-291434Q03519Espacenet
EP 4641201 A22025-10-299801Q03519Espacenet
JP 2025529142 A2025-09-044580Q03519Espacenet
US 12371689 B22025-07-294580Q03519Espacenet
JP 2025519096 A2025-06-241434Q03519Espacenet

1 to 10 of 55

See all 55 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,916

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTAP2 papersNewest fiscal year
P30CA008748Cancer Center Support Grant202025
R01AI044115Influences of HLA Class I Polymorphisms on immune responses162025
P30CA016672Cancer Center Support Grant142025
P30CA047904Cancer Center Support Grant102025
P50CA097190Head and Neck Cancer SPORE82025
ZIABC010030Biochemical Analysis of Multidrug Resistance-linked Transport Proteins62025
P01CA019014Viral Oncogenesis, Latency, and Replication52025
P30CA016056Roswell Park Cancer Center Support Grant52025
UL1TR001863Yale Clinical and Translational Science Award52025
P01CA022443Molecular Biology and Genetics of Human Tumor Viruses42025

1 to 10 of 1,916Source NIH's project files

See all 1,916 nih grants

Papers2,915

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
DNA methylation signatures distinguish gout from asymptomatic hyperuricaemia and converge with genetic risk at immune-metabolic loci.Ann Rheum Dis202642810907PubTator, text miningPubMed
Integrated multi-omics analysis of post-translational modifications in head and neck squamous cell carcinoma: elucidating x-ray and carbon ion irradiation effects.Precis Radiat Oncol202642807604PubTator, text miningPubMed
Epigenome-wide placental methylation landscapes in relation to antenatal depressive symptoms.Neurochem Int202642744221PubTator, text miningPubMed
Oncogenic Signalling and Immune Checkpoint Crosstalk in Cancer: Emerging Targets and Precision Therapeutic Strategies.Curr Drug Targets202642669994PubTator, text miningPubMed
Immunotherapy Resistance in dMMR/MSI-H Colorectal Cancer: Unraveling Mechanisms and Exploring Overcoming Strategies.J Immunol Res202642590903PubTator, text miningPubMed
Primary and acquired resistance to immunotherapy in NSCLC.Front Immunol202642495623PubTator, text miningPubMed
Spatial Transcriptomics of Immune Cell Distribution in Non-Small Cell Lung Cancer Identifies Tertiary Lymphoid Structures and Its Density and Area Fraction Were Associated with Neoadjuvant Therapy Response.
Cancers (Basel)202642449683PubTator, text miningPubMed
Systematic discovery of pathogen effector functions across human pathogens and pathways.Cell202642379168PubTator, text miningPubMed
Convergence in Pruning and Circadian Regulation in Obsessive-Compulsive Disorder and Allergic Diseases: Evidence From a Secondary Genome-Wide Analysis.Cureus202642222623PubTator, text miningPubMed
NSCLC brain metastases exhibit reduced HLA-I antigen presentation machinery and immune evasion independent of IFNγ signaling defects.Mol Cancer202642210261PubTator, text miningPubMed

1 to 10 of 2,915

See all 2,915 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6891

GET https://conductscience.org/api/genes/v1/6891/patents?page=2