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Gene · 6895

TARBP2: TARBP2 subunit of RISC loading complex

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TARBP2: TARBP2 subunit of RISC loading complex. Genes, record 6895. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6895

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Gene

Symbol
TARBP2
HGNC
Name
TARBP2 subunit of RISC loading complex
HGNC
NCBI Gene ID
6895
NCBI Gene
HGNC ID
HGNC:11569
HGNC
Ensembl
ENSG00000139546
NCBI Gene
Aliases
LOQS, TRBP, TRBP1, TRBP2, Trbp
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q15633RISC-loading complex subunit TARBP236610Ensembl, GeneID, HGNC

Source UniProt

Patents23

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1466449Q15633Espacenet
EP 4641201 A22025-10-292179Q15633Espacenet
JP 2025517969 A2025-06-122179Q15633Espacenet
US 12023371 B22024-07-024959Q15633Espacenet
US 11446398 B22022-09-2086723Q15633Espacenet
JP 2022524081 A2022-04-27189694Q15633Espacenet
US 11078247 B22021-08-0311309Q15633Espacenet
US 10925935 B22021-02-234959Q15633Espacenet
JP 2019054813 A2019-04-11246884Q15633Espacenet
US 10155029 B22018-12-184959Q15633Espacenet

1 to 10 of 23

See all 23 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants898

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTARBP2 papersNewest fiscal year
P30CA016672Cancer Center Support Grant102025
P30CA008748Cancer Center Support Grant52025
P30CA033572Cancer Center Support Grant42025
P50CA127001SPORE in Brain Cancer42025
P01CA100730Retrovirus Models of Cancer32025
P30CA010815Consolidated Basic Cancer Research Program32025
P30CA016056Roswell Park Cancer Center Support Grant32025
P01CA092584Structural Cell Biology of DNA Repair Machines22025
P30CA016058Cancer Center Support Grant22025
P30CA093373Cancer Center Support Grant P3022025

1 to 10 of 898Source NIH's project files

See all 898 nih grants

Papers1,452

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Integrated analysis of MYH6, MYH7, and MYH7B expression and their associated microRNAs in human end-stage heart failure.Front Cardiovasc Med202642630156PubTator, text miningPubMed
Steroid-Resistant Idiopathic Nephrotic Syndrome Reveals a Distinct Maladaptive Molecular State.Kidney Int Rep202642375703PubTator, text miningPubMed
Revealing the function and mechanism of piRNA-related genes in bladder cancer through single-cell sequencing and methylation analyses and construction of prognostic features based on consensus clustering.
Curr Urol202641668898PubTator, text miningPubMed
Staufen dsRNA-binding domain as modules to design bifunctional antibodies for siRNA delivery.Nucleic Acids Res202641569158PubTator, text miningPubMed
The Potential of Noncoding RNAs-siRNAs in Cancer Research and Therapy: Challenges and Solutions.Exp Suppl202641479113PubTator, text miningPubMed
Disrupted miRNA Biogenesis Machinery Reveals Common Molecular Pathways and Diagnostic Potential in MDS and AML.Biomedicines202541463093PubTator, text miningPubMed
A 3,4-diamino-substituted coumarin derivative as a TRBP inhibitor suppresses tumor growth in breast cancer by inducing cellular senescence.Am J Cancer Res202541244116PubTator, text miningPubMed
Targeting RNA-binding proteins with small molecules: perspectives and challenges.Front Chem202541112581PubTator, text miningPubMed
Emerging biomarkers for early cancer detection and diagnosis: challenges, innovations, and clinical perspectives.Eur J Med Res202540826140PubTator, text miningPubMed
TRBP modulates RLR signaling by inhibiting PKR-mediated antiviral stress granule formation.Sci Rep202540593223PubTator, text miningPubMed

1 to 10 of 1,452

See all 1,452 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6895

GET https://conductscience.org/api/genes/v1/6895/patents?page=2