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TBX1: T-box transcription factor 1

1 protein, 15 patents, 0 drugs, 0 trials, 3,087 NIH grants and 4,826 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolTBX1HGNC
NameT-box transcription factor 1HGNC
NCBI Gene ID6899NCBI Gene
HGNC IDHGNC:11592HGNC
EnsemblENSG00000184058NCBI Gene
AliasesCAFS, CATCH22, CTHM, DGCR, DGS, DORV, TBX1C, TGA, VCF, VCFSNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
O43435T-box transcription factor TBX13981Ensembl, GeneID, HGNCUniProt

Patents 15

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1466578O43435Espacenet
JP 2025147176 A2025-10-0615714O43435Espacenet
JP 2025028160 A2025-02-2815714O43435Espacenet
KR 1020250010750 A2025-01-2115714O43435Espacenet
JP 2024151104 A2024-10-2423O43435Espacenet
JP 2024109657 A2024-08-1415553O43435Espacenet
US 11446398 B22022-09-2087247O43435Espacenet
JP 2022524081 A2022-04-27190218O43435Espacenet
JP 2021536249 A2021-12-2715907O43435Espacenet
JP 2021507703 A2021-02-2515867O43435Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3087

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant192,025NIH's project files
ZIABC010598Human Immune Responses to Tumor Antigens for Cancer Immunotherapy192,025NIH's project files
ZIABC010944Strategies for Cancer Immunotherapy Development: Preclinical Studies132,025NIH's project files
P01HL141084Multiscale Systems to Elucidate Susceptibility and Cardioprotective Mechanisms in Cardio-oncology112,025NIH's project files
R01HL130020Elucidating Mechanism of Cardiac Fibrosis with Cell Village of Pooled Human iPSCs102,025NIH's project files
R01MH099660Postnatal mechanisms of cognitive development in mice102,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award92,025NIH's project files
ZIABC010666Cancer Immunotherapy82,025NIH's project files
P30CA014520UW Comprehensive Cancer Center Support72,025NIH's project files
P30CA016672Cancer Center Support Grant72,025NIH's project files

Papers 4826

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42754054PubTator, text miningPubMed
42750915PubTator, text miningPubMed
42748591PubTator, text miningPubMed
42671172PubTator, text miningPubMed
42635044PubTator, text miningPubMed
42634066PubTator, text miningPubMed
42601506PubTator, text miningPubMed
42587758PubTator, text miningPubMed
42571860PubTator, text miningPubMed
42559592PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license