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Gene · 6909

TBX2: T-box transcription factor 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TBX2: T-box transcription factor 2. Genes, record 6909. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6909

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Gene

Symbol
TBX2
HGNC
Name
T-box transcription factor 2
HGNC
NCBI Gene ID
6909
NCBI Gene
HGNC ID
HGNC:11597
HGNC
Ensembl
ENSG00000121068
NCBI Gene
Aliases
VETD
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q13207T-box transcription factor TBX27120Ensembl, GeneID, HGNC

Source UniProt

Patents28

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-191024Q13207Espacenet
EP 4640849 A22025-10-29112Q13207Espacenet
EP 4641201 A22025-10-29711Q13207Espacenet
JP 2025147176 A2025-10-0615719Q13207Espacenet
JP 2025519096 A2025-06-24112Q13207Espacenet
JP 2025517969 A2025-06-12711Q13207Espacenet
JP 2025517970 A2025-06-121024Q13207Espacenet
JP 2025028160 A2025-02-2815719Q13207Espacenet
KR 1020250010750 A2025-01-2115719Q13207Espacenet
JP 2024123008 A2024-09-108608Q13207Espacenet

1 to 10 of 28

See all 28 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,128

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTBX2 papersNewest fiscal year
P30CA008748Cancer Center Support Grant62025
P30ES010126UNC Center for Environmental Health and Susceptibility52025
P40OD010440Caenorhabditis Genetics Center42025
P30CA014520UW Comprehensive Cancer Center Support32025
P30CA016056Roswell Park Cancer Center Support Grant32025
P30CA016672Cancer Center Support Grant32025
P50CA116201Mayo Clinic Breast Cancer SPORE32025
R35CA220500Discovering mechanisms of neuroblastoma tumorigenesis to improve patient outcomes32025
UL1TR001881UCLA Clinical and Translational Science Institute32025
K12HD000849Reproductive Scientist Development Program22025

1 to 10 of 1,128Source NIH's project files

See all 1,128 nih grants

Papers1,285

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Multi-omic analysis reveals maturation programs in human pluripotent stem cell-derived cardiomyocytes during long-term culture.J Mol Cell Cardiol202642826860PubTator, text miningPubMed
A TBX2-HLX Regulatory Axis Is Associated with Advanced Prostate Cancer.Biomedicines202642652246PubTator, text miningPubMed
The regulation of endothelial-to-mesenchymal transition in endocardial cushion development: Signaling pathways and transcription factors.Differentiation202642600378PubTator, text miningPubMed
Aberrant O-glycosylation genes and miR-21-5p targets define a molecular signature of tumor aggressiveness in triple-negative breast cancer.Glycobiology202642348735PubTator, text miningPubMed
The Roles of Tbx2 in Cochlear Development and Auditory Function.Neurosci Bull202642262705PubTator, text miningPubMed
Conserved roles of GATA4 and its target gene TBX2 in regulation of human cardiogenesis.Biol Open202642136535PubTator, text miningPubMed
Investigation of ELF5, KIF18A, NPTX1 and COL23A1 genes in the pathophysiology of indirect inguinal hernia in children.Pediatr Surg Int202641925903PubTator, text miningPubMed
Regulatory T cells in axial spondyloarthritis.Commun Biol202641917236PubTator, text miningPubMed
Corrigendum to "Generation of induced pluripotent stem cell line IRDWCHi001-A from a patient with hearing loss and nystagmus carrying the heterozygous TBX2 c.977delA (p.D326Afs*42) mutation" [Stem Cell Res. 90 (2026) 103906].
Stem Cell Res202641886979PubTator, text miningPubMed
The Dual Role of Extracellular Vesicles in Aging and Age-Related Diseases: Pathophysiology and Therapeutic Potential.Int J Nanomedicine202641810000PubTator, text miningPubMed

1 to 10 of 1,285

See all 1,285 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6909

GET https://conductscience.org/api/genes/v1/6909/patents?page=2