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Gene · 6923

ELOB: elongin B

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ELOB: elongin B. Genes, record 6923. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6923

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Gene

Symbol
ELOB
HGNC
Name
elongin B
HGNC
NCBI Gene ID
6923
NCBI Gene
HGNC ID
HGNC:11619
HGNC
Ensembl
ENSG00000103363
NCBI Gene
Aliases
SIII, TCEB2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q15370Elongin-B118230Ensembl, GeneID, HGNC

Source UniProt

Patents57

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4661970 A12025-12-1762147Q15370Espacenet
EP 4650780 A22025-11-1912077Q15370Espacenet
JP 2025517970 A2025-06-1212077Q15370Espacenet
EP 4253412 A22023-10-0414Q15370Espacenet
JP 2023123507 A2023-09-05355Q15370Espacenet
US 11564998 B22023-01-317200Q15370Espacenet
US 11492404 B22022-11-0814Q15370Espacenet
US 11446398 B22022-09-2089619Q15370Espacenet
US 11339220 B22022-05-2414Q15370Espacenet
JP 2022524081 A2022-04-27192590Q15370Espacenet

1 to 10 of 57

See all 57 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,082

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleELOB papersNewest fiscal year
R01AG011085Ubiquitin‐mediated proteolysis and cell cycle control112025
ZIABC011028Clinical Studies of the Molecular Genetic Basis of Kidney Cancer112025
ZIABC011038Molecular Therapeutics of Kidney Cancer: VHL Gene and Fumarate Hydratase Gene102025
ZIABC011043Molecular Therapeutics of Kidney Cancer: MET Gene and BHD Gene102025
P30CA016672Cancer Center Support Grant92025
ZIDBC011089Clinical Nursing and Data Management Core92025
P30CA021765Cancer Center Support Grant (CCSG)82025
T32AI060537Integrative Microbiology Program72025
P30AI027763UCSF-Bay Area Center for AIDS Research62025
P30CA016086Cancer Center Support Grant62025

1 to 10 of 1,082Source NIH's project files

See all 1,082 nih grants

Papers1,377

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Chemical tools for BAZ2A/B biology: discovery of dual and BAZ2B-selective PROTAC degraders.RSC Med Chem202642626597PubTator, text miningPubMed
Recent advances in etiology and treatment of von Hippel-Lindau Disease (VHLD).Cancer Metastasis Rev202642593521PubTator, text miningPubMed
Elongin B orchestrates chromatin and transcriptional programs in H3K27M-mutant diffuse midline glioma.bioRxiv202642239282PubTator, text miningPubMed
A conserved mechanism for stabilization of viral innate immune antagonists via interaction with Elongin BC.Proc Natl Acad Sci U S A202642234532PubTator, text miningPubMed
Structure of the E3 ligase CRL2ZYG11B with substrates reveals the molecular basis for N-degron recognition and ubiquitination.Cell Rep202642224082PubTator, text miningPubMed
Targeting the Elongin BC-BC-Box Interface: Structural Insights, Peptidic Disruptors and Emerging Small-Molecule Strategies.Chem Biol Drug Des202642070964PubTator, text miningPubMed
Proliferation and Apoptosis Adaptor Protein 15 (PEA15), a Potential Oncogenic Regulator of VHL and HIF1A Identified through Proteomic Analysis in Hepatocellular Carcinoma.Cancer Commun (Lond)202641958708PubTator, text miningPubMed
Structures of ZYG11B-EloB-EloC-substrate complex reveal mechanisms of CRL2ZYG11B assembly and function.Nat Commun202641917018PubTator, text miningPubMed
Atomic-Scale Mapping of Interfacial Water on Oxide Surfaces via Proton-Resolved NMR and Ab Initio Simulations.J Am Chem Soc202641837765PubTator, text miningPubMed
Emerging Protein Targets in Triple-Negative Breast Cancer: Beyond Conventional Therapy.Cancers (Basel)202641749871PubTator, text miningPubMed

1 to 10 of 1,377

See all 1,377 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6923

GET https://conductscience.org/api/genes/v1/6923/patents?page=2