ConductScience.org, home

Gene · 6926

TBX3: T-box transcription factor 3

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. TBX3: T-box transcription factor 3. Genes, record 6926. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6926

On this page

Gene

Symbol
TBX3
HGNC
Name
T-box transcription factor 3
HGNC
NCBI Gene ID
6926
NCBI Gene
HGNC ID
HGNC:11602
HGNC
Ensembl
ENSG00000135111
NCBI Gene
Aliases
TBX3-ISO, UMS, XHL
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O15119T-box transcription factor TBX37431Ensembl, GeneID, HGNC

Source UniProt

Patents38

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1466597O15119Espacenet
EP 4641201 A22025-10-291245O15119Espacenet
JP 2025147176 A2025-10-0615723O15119Espacenet
JP 2025517969 A2025-06-121245O15119Espacenet
JP 2025028160 A2025-02-2815723O15119Espacenet
KR 1020250010750 A2025-01-2115723O15119Espacenet
JP 2024109657 A2024-08-1415562O15119Espacenet
US 11920164 B22024-03-05129O15119Espacenet
US 11446398 B22022-09-2087273O15119Espacenet
JP 2022524081 A2022-04-27190244O15119Espacenet

1 to 10 of 38

See all 38 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,256

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTBX3 papersNewest fiscal year
P30CA008748Cancer Center Support Grant302025
P30CA016672Cancer Center Support Grant142025
P30DK063491Diabetes Research Center (DRC)102025
R01HL086694From GWAS loci to blood pressure genes, variants & mechanisms - Renewal102025
R01HL092577IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVAL102025
P30CA068485Cancer Center Support Grant92025
P30DK026743UCSF Liver Center72025
UL1TR001881UCLA Clinical and Translational Science Institute72025
ZIAHL006001Framingham Project/Levy72025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant62025

1 to 10 of 2,256Source NIH's project files

See all 2,256 nih grants

Papers2,253

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Metformin Drives Hepatocyte Molecular Reprogramming Through a Fibroblast Growth Factor 1-Fibroblast Growth Factor Receptor 4-T-Box Transcription Factor 3 Axis in Cholestasis.Cell Mol Gastroenterol Hepatol202642822673PubTator, text miningPubMed
Genetic loci responsible for atrioventricular block in children.Front Cell Dev Biol202642798645PubTator, text miningPubMed
Molecular Classifications and Candidate Biomarkers for Personalizing BCG Therapy in Non-Muscle-Invasive Bladder Cancer.Biomedicines202642792838PubTator, text miningPubMed
Primary breast acinic cell-like carcinoma: A report of three cases and a review of the literature.Ann Diagn Pathol202642777411PubTator, text miningPubMed
Retraction: T-box Transcription Factor Tbx3 Contributes to Human Hepatocellular Carcinoma Cell Migration and Invasion by Repressing E-Cadherin Expression.Oncol Res202642769425PubTator, text miningPubMed
Breast cancer ovarian metastases show increased activity of GPCR pathways.bioRxiv202642619866PubTator, text miningPubMed
Genomic Landscape and Perinatal Outcomes of Fetal Polydactyly: A Retrospective Cohort Study Integrating CNV-seq and Trio-ES.Prenat Diagn202642390887PubTator, text miningPubMed
Genetic Profiling of Primary Versus Metastatic Ewing Sarcoma for Therapeutic Target Identification.Life (Basel)202642355429PubTator, text miningPubMed
Single-cell profiling reveals a novel CAF subpopulation linking stromal heterogeneity to immune suppression in breast cancer subtypes.J Transl Med202642351142PubTator, text miningPubMed
Spatiotemporal Profiling Defines the Epithelial and Mesenchymal Transition Window in Embryonic Lung Morphogenesis.J Dev Biol202642346508PubTator, text miningPubMed

1 to 10 of 2,253

See all 2,253 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6926

GET https://conductscience.org/api/genes/v1/6926/patents?page=2