ConductScience.org, home

Library / Genes

HNF1A: HNF1 homeobox A

1 protein, 12 patents, 0 drugs, 0 trials, 4,214 NIH grants and 7,698 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolHNF1AHGNC
NameHNF1 homeobox AHGNC
NCBI Gene ID6927NCBI Gene
HGNC IDHGNC:11621HGNC
EnsemblENSG00000135100NCBI Gene
AliasesHNF-1-alpha, HNF-1A, HNF1, HNF1alpha, HNF1α, IDDM20, LFB1, MODY3, TCF-1, TCF1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P20823Hepatocyte nuclear factor 1-alpha6316Ensembl, GeneID, HGNCUniProt

Patents 12

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1449249P20823Espacenet
EP 4640849 A22025-10-29192P20823Espacenet
EP 4641201 A22025-10-291244P20823Espacenet
JP 2025519096 A2025-06-24192P20823Espacenet
JP 2025517969 A2025-06-121244P20823Espacenet
US 11446398 B22022-09-2038738P20823Espacenet
JP 2022524081 A2022-04-27141709P20823Espacenet
JP 2019054813 A2019-04-11229684P20823Espacenet
JP 2017121241 A2017-07-13229684P20823Espacenet
JP 2015516143 A2015-06-08229684P20823Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4214

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant372,025NIH's project files
P30DK020595Diabetes Research and Training Center352,025NIH's project files
P30DK063491Diabetes Research Center (DRC)232,025NIH's project files
P30CA008748Cancer Center Support Grant222,025NIH's project files
P30DK036836Diabetes Research Center172,025NIH's project files
P30DK020572Michigan Diabetes Research Center (MDRC)162,025NIH's project files
P30DK026743UCSF Liver Center142,025NIH's project files
R01AI112579Regulation of T cell exhaustion via 3D chromatin architecture142,025NIH's project files
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant122,025NIH's project files
R01AI121080CTCF in CD8 T cell homeostasis and anti-viral/tumor immunity122,025NIH's project files

Papers 7698

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42827194PubTator, text miningPubMed
42823492PubTator, text miningPubMed
42786432PubTator, text miningPubMed
42733542PubTator, text miningPubMed
42728778PubTator, text miningPubMed
42685389PubTator, text miningPubMed
42677197PubTator, text miningPubMed
42675222PubTator, text miningPubMed
42663735PubTator, text miningPubMed
42639261PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license