ConductScience.org, home

Library / Genes

HNF1B: HNF1 homeobox B

1 protein, 36 patents, 0 drugs, 0 trials, 2,681 NIH grants and 4,765 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolHNF1BHGNC
NameHNF1 homeobox BHGNC
NCBI Gene ID6928NCBI Gene
HGNC IDHGNC:11630HGNC
EnsemblENSG00000275410NCBI Gene
AliasesADTKD3, FJHN, HNF-1-beta, HNF-1B, HNF1beta, HNF1β, HNF2, HPC11, LF-B3, LFB3, MODY5, RCAD, T2D, TCF-2, TCF2, VHNF1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P35680Hepatocyte nuclear factor 1-beta5573Ensembl, GeneID, HGNCUniProt

Patents 36

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2025147176 A2025-10-0615106P35680Espacenet
JP 2025028160 A2025-02-2815106P35680Espacenet
KR 1020250010750 A2025-01-2115106P35680Espacenet
JP 2024123008 A2024-09-106504P35680Espacenet
JP 2024109657 A2024-08-1414945P35680Espacenet
US 11446398 B22022-09-2038753P35680Espacenet
US 11446398 B22022-09-2038759P35680Espacenet
JP 2022524081 A2022-04-27141724P35680Espacenet
JP 2022524081 A2022-04-27141730P35680Espacenet
JP 2021536249 A2021-12-2715299P35680Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2681

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant492,025NIH's project files
P30DK020595Diabetes Research and Training Center222,025NIH's project files
P50CA136393Use of microfluidic tumor cultures to enable clinical trials of therapies for ovarian cancer222,025NIH's project files
P30CA016672Cancer Center Support Grant212,025NIH's project files
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant202,025NIH's project files
P30DK036836Diabetes Research Center152,025NIH's project files
ZIACP010126Hormone-Related Cancers152,025NIH's project files
R01DK042921Regulation of Kidney-Specific Gene Expression142,025NIH's project files
R01DK062370Identifying Genes for Type 2 Diabetes: FUSION112,025NIH's project files
P30CA071789University of Hawaii Cancer Center CCSG102,025NIH's project files

Papers 4765

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42817172PubTator, text miningPubMed
42780506PubTator, text miningPubMed
42772450PubTator, text miningPubMed
42760837PubTator, text miningPubMed
42739594PubTator, text miningPubMed
42739200PubTator, text miningPubMed
42730770PubTator, text miningPubMed
42723985PubTator, text miningPubMed
42650924PubTator, text miningPubMed
42613169PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license