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TCF7: transcription factor 7

1 protein, 24 patents, 0 drugs, 0 trials, 3,885 NIH grants and 5,273 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolTCF7HGNC
Nametranscription factor 7HGNC
NCBI Gene ID6932NCBI Gene
HGNC IDHGNC:11639HGNC
EnsemblENSG00000081059NCBI Gene
AliasesTCF-1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P36402Transcription factor 73840Ensembl, GeneID, HGNCUniProt

Patents 24

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4754236 A12026-06-10187P36402Espacenet
JP 2025506185 A2025-03-0782P36402Espacenet
EP 4479067 A22024-12-2582P36402Espacenet
US 11446398 B22022-09-2089794P36402Espacenet
JP 2022524081 A2022-04-27192765P36402Espacenet
WO 2020020471 A12020-01-3017P36402Espacenet
JP 2019033757 A2019-03-0724784P36402Espacenet
JP 2017132796 A2017-08-03276P36402Espacenet
JP 2017123847 A2017-07-2024784P36402Espacenet
US 9504734 B22016-11-296168P36402Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3885

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant592,025NIH's project files
P30CA016672Cancer Center Support Grant312,025NIH's project files
R01AI112579Regulation of T cell exhaustion via 3D chromatin architecture292,025NIH's project files
R01AI121080CTCF in CD8 T cell homeostasis and anti-viral/tumor immunity252,025NIH's project files
U19AI082630Durable Alteration of the Human Immune system after Infection or Immunotherapy252,025NIH's project files
P30CA086862Cancer Center Support Grant242,025NIH's project files
U19AI057266Vaccine and Infection Induced Immunity in the Young and Aged232,025NIH's project files
P51OD011132Emory National Primate Research Center202,025NIH's project files
P30CA016520Abramson Cancer Center Support Grant172,025NIH's project files
R01HL117913The NOTCH Signaling Pathway in Large Vessel Vasculitis172,025NIH's project files

Papers 5273

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42826713PubTator, text miningPubMed
42824457PubTator, text miningPubMed
42810908PubTator, text miningPubMed
42810560PubTator, text miningPubMed
42806659PubTator, text miningPubMed
42803969PubTator, text miningPubMed
42779625PubTator, text miningPubMed
42770904PubTator, text miningPubMed
42765973PubTator, text miningPubMed
42749792PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license