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Gene · 6938

TCF12: transcription factor 12

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TCF12: transcription factor 12. Genes, record 6938. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6938

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Gene

Symbol
TCF12
HGNC
Name
transcription factor 12
HGNC
NCBI Gene ID
6938
NCBI Gene
HGNC ID
HGNC:11623
HGNC
Ensembl
ENSG00000140262
NCBI Gene
Aliases
CRS3, HEB, HH26, HTF4, HsT17266, TCF-12, bHLHb20, p64
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q99081Transcription factor 126822Ensembl, GeneID, HGNC

Source UniProt

Patents55

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1467359Q99081Espacenet
JP 2026004568 A2026-01-1467366Q99081Espacenet
EP 4650780 A22025-11-192626Q99081Espacenet
EP 4641201 A22025-10-292212Q99081Espacenet
JP 2025147176 A2025-10-0613041Q99081Espacenet
JP 2025147176 A2025-10-0613044Q99081Espacenet
JP 2025147176 A2025-10-0615727Q99081Espacenet
JP 2025529142 A2025-09-047852Q99081Espacenet
US 12371689 B22025-07-297852Q99081Espacenet
JP 2025517969 A2025-06-122212Q99081Espacenet

1 to 10 of 55

See all 55 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,581

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTCF12 papersNewest fiscal year
P30CA008748Cancer Center Support Grant112025
P01AI102853Molecular Basis for γδ T Lineage Specification72025
P30CA068485Cancer Center Support Grant72025
P30CA016672Cancer Center Support Grant62025
P30DK058404Molecular and Cellular Basis for Digestive Diseases62025
P30CA021765Cancer Center Support Grant (CCSG)52025
P30CA091842Cancer Center Support Grant52025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant52025
P30CA016058Cancer Center Support Grant42025
P50CA217694SPORE in Soft Tissue Sarcoma42025

1 to 10 of 1,581Source NIH's project files

See all 1,581 nih grants

Papers1,800

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
K17 hi Hair Follicle Cells Orchestrate Psoriatic Inflammation Through S100A1-Dependent Signaling.Br J Dermatol202642817581PubTator, text miningPubMed
Transcription factor 12 promotes acute myeloid leukemia cell survival by regulating mitochondrial function and ROS.Autoimmunity202642721011PubTator, text miningPubMed
Injured proximal tubule-driven paracrine signaling promotes lipid-associated macrophage expansion and chondroitin sulfate biosynthesis via PPARG/TCF12 in diabetic kidney disease.Front Immunol202642694185PubTator, text miningPubMed
Transcript-aware rare genetic variant association analyses of cardiopulmonary traits in participants from the All of Us Research Program.Nat Commun202642642362PubTator, text miningPubMed
Genetic Etiology and Neurodevelopmental Outcomes in Children With Craniosynostosis: A 15-Year Single-Center Retrospective Study.J Craniofac Surg202642607197PubTator, text miningPubMed
Retrospective assessment of TCF12 expression in early invasive breast cancer and ovarian cancer: prognostic implications and biological insights.Pathology202642552187PubTator, text miningPubMed
miR-770-5p regulates KDM5B and links its nuclear localization to HER2 signaling in trastuzumab-resistant breast cancer.Mol Cell Biochem202642474975PubTator, text miningPubMed
Genomic landscape of rare variants in a Chinese autism cohort and discovery of novel risk genes.Mol Psychiatry202642463903PubTator, text miningPubMed
LncRNA GATA3-AS1-mediated miR-2116-5p interaction modulates TCF12 and contributes to podocyte dysfunction in childhood nephrotic syndrome.Clinics (Sao Paulo)202642462511PubTator, text miningPubMed
Clinical and molecular characterization of TCF12 variants in an Asian pediatric cohort with craniosynostosis.BMC Med Genomics202642443919PubTator, text miningPubMed

1 to 10 of 1,800

See all 1,800 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6938

GET https://conductscience.org/api/genes/v1/6938/patents?page=2