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Gene · 6947

TCN1: transcobalamin 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TCN1: transcobalamin 1. Genes, record 6947. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6947

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Gene

Symbol
TCN1
HGNC
Name
transcobalamin 1
HGNC
NCBI Gene ID
6947
NCBI Gene
HGNC ID
HGNC:11652
HGNC
Ensembl
ENSG00000134827
NCBI Gene
Aliases
HC, TC-1, TC1, TCI
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P20061Transcobalamin-14332Ensembl, GeneID, HGNC

Source UniProt

Patents45

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026067851 A2026-04-21321P20061Espacenet
JP 2026004568 A2026-01-1467337P20061Espacenet
EP 4650780 A22025-11-191627P20061Espacenet
EP 4641201 A22025-10-291232P20061Espacenet
EP 4641203 A22025-10-2949P20061Espacenet
JP 2025147176 A2025-10-0613052P20061Espacenet
JP 2025529142 A2025-09-047853P20061Espacenet
US 12371689 B22025-07-297853P20061Espacenet
JP 2025517967 A2025-06-1249P20061Espacenet
JP 2025517969 A2025-06-121232P20061Espacenet

1 to 10 of 45

See all 45 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,067

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTCN1 papersNewest fiscal year
P30MH092177Comprehensive NeuroHIV Center82025
T32MH079785Interdisciplinary And Translational Research Training In Neurohiv52025
ZIAHG000167The contribution folate and vitamin B12 genes to disease.42025
P30AI027757University of Washington/Fred Hutch Center for AIDS Research32025
P30AI027767UAB Center for AIDS Research (CFAR)32025
P30AI110527Tennessee Center for AIDS Research (TN-CFAR)32025
R01DK112812Neural Mechanisms of Nausea, Vomiting, and Energy Dysregulation32025
P30AI050410The University of North Carolina Center for AIDS Research22025
P30AI117970District of Columbia Center for AIDS Research22025
P30AR075043University of Michigan Skin Biology and Diseases Resource-based Center22025

1 to 10 of 1,067Source NIH's project files

See all 1,067 nih grants

Papers1,787

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
TFPI-high myofibroblast states and a meta-program-related five-gene prognostic signature in breast cancer.Biomol Biomed202642721217PubTator, text miningPubMed
The TCN1 Paradox: Unraveling the Dual Role of Transcobalamin I in Colorectal Cancer-From Metabolic Regulation to Oncogenic Signaling.Cancer Manag Res202642577958PubTator, text miningPubMed
Photoinduced Charge-Transfer Suppresses Triplet Formation Efficiency in Thiocoumarins: Evidence from Ultrafast Spectroscopy and Theoretical Calculations.J Phys Chem A202642397713PubTator, text miningPubMed
Histone H3K18 lactylation promotes malignancy progression in non-small cell lung cancer through TCN1 upregulation.J Mol Histol202642315765PubTator, text miningPubMed
Hypopigmented Mycosis Fungoides With Childhood-Onset and Middle-Aged Onset: Two Case Reports Focusing on the Cutaneous Immune Microenvironment.J Dermatol202642261000PubTator, text miningPubMed
Plasma Proteins Associated with Whole Grains and Fiber Intake in the Cardiovascular Health Study (CHS) and the Atherosclerosis Risk in Communities (ARIC) Study.J Nutr202642235824PubTator, text miningPubMed
GAP mimetic activity of pan-Ras TCI daraxonrasib synergizes with K-Ras Switch-II pocket inhibition.Biol Chem202642030031PubTator, text miningPubMed
Machine learning-based programmed cell death gene signature for prognosis and drug sensitivity in breast cancer.Oncol Lett202642027644PubTator, text miningPubMed
Predicting Clinical Outcomes and Immunotherapy Responses in Lung Adenocarcinoma Based on Nicotine Response Characteristics.Curr Med Chem202641968544PubTator, text miningPubMed
Molecular heterogeneity of HPV-associated cancers and strategies to overcome treatment resistance.Cancer Heterog Plast202641938668PubTator, text miningPubMed

1 to 10 of 1,787

See all 1,787 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6947

GET https://conductscience.org/api/genes/v1/6947/patents?page=2