Gene · 6998
CRIPTO3: cripto, EGF-CFC family member 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CRIPTO3: cripto, EGF-CFC family member 3. Genes, record 6998. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6998
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P51864 | Protein CRIPTO3 | 188 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents45
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| US 11400116 B2 | 2022-08-02 | 7466 | P51864 | Espacenet |
| US 8673303 B2 | 2014-03-18 | 2 | P51864 | Espacenet |
| US 8586006 B2 | 2013-11-19 | 55421 | P51864 | Espacenet |
| US 8586006 B2 | 2013-11-19 | 55422 | P51864 | Espacenet |
| JP 2013172712 A | 2013-09-05 | 117 | P51864 | Espacenet |
| JP 2013140167 A | 2013-07-18 | 117 | P51864 | Espacenet |
| US 8349324 B2 | 2013-01-08 | 2 | P51864 | Espacenet |
| US 8021661 B2 | 2011-09-20 | 7 | P51864 | Espacenet |
| US 8003763 B2 | 2011-08-23 | 2 | P51864 | Espacenet |
| EP 2316486 A2 | 2011-05-04 | 2 | P51864 | Espacenet |
1 to 10 of 45
See all 45 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,094
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CRIPTO3 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 9 | 2025 |
| R01HL063199 | The role of beta 2 integrins in macrophage fusion | 8 | 2025 |
| ZIAHL006223 | The role of the intracellular complement system - the complosome - in Th1 biology | 7 | 2025 |
| R01DK084195 | Translating oral CD11b agonist as a novel therapeutic for lupus nephritis | 6 | 2025 |
| ZIABC010440 | Protein Structure, Stability, and Amyloid Formation | 6 | 2025 |
| ZIABC010441 | Biomolecular Recognition and Binding Mechanisms | 6 | 2025 |
| P30CA014195 | Cancer Center Support Grant (CCSG) | 5 | 2025 |
| ZIAHL006222 | The role of the intracellular complement system - the complosome - in monocytes | 5 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 3 | 2025 |
| P30CA015083 | Mayo Clinic Comprehensive Cancer Center Support Grant | 3 | 2025 |
1 to 10 of 2,094Source NIH's project files
See all 2,094 nih grantsPapers3,187
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Microglial GPR56 in synaptic pruning: mechanisms, comparative receptor biology, and context-dependent roles in brain disorders. | Biochim Biophys Acta Mol Cell Res | 2026 | 42826818 | PubTator, text mining | PubMed |
| Complement-mediated synaptic loss in inflammatory depression: mechanisms and therapeutic prospects. | Brain Behav Immun | 2026 | 42800570 | PubTator, text mining | PubMed |
| Neuroimmune Dysregulation and Synaptic Pruning in Autism Spectrum Disorder. | Biology (Basel) | 2026 | 42737971 | PubTator, text mining | PubMed |
| Neuroimmune interactions: from molecular mechanisms to therapeutic targets. | Mol Biomed | 2026 | 42714778 | PubTator, text mining | PubMed |
| The complement system in the pathophysiology and treatment of depression: From synaptic pruning to pharmacological targeting. | Pharmacol Res | 2026 | 42668072 | PubTator, text mining | PubMed |
| Range-Wide Geographic Variation of Major Gene Resistance (Cr3) to White Pine Blister Rust in Pinus strobiformis (Southwestern White Pine). | Phytopathology | 2026 | 42571661 | PubTator, text mining | PubMed |
| Structural characterization and immunomodulatory activity of sulfated polysaccharides from the green microalgae Tetraselmis suecica. | Fitoterapia | 2026 | 42486285 | PubTator, text mining | PubMed |
| Complement dysregulation during the early phases of synucleinopathy. | Acta Neuropathol | 2026 | 42477211 | PubTator, text mining | PubMed |
| NMR investigation of conformational heterogeneity in FOXO4 CR2C binding to the MLL site of CBP KIX. | J Magn Reson | 2026 | 42472485 | PubTator, text mining | PubMed |
| Injectable Hydrogel-Based Delivery of Soluble Cripto Protein Enhances Repair After Skeletal Muscle Injury. | ACS Biomater Sci Eng | 2026 | 42284448 | PubTator, text mining | PubMed |
1 to 10 of 3,187
See all 3,187 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/6998
GET https://conductscience.org/api/genes/v1/6998/patents?page=2